Multiple U2AF65 binding sites within SF3b155: thermodynamic and spectroscopic characterization of protein-protein interactions among pre-mRNA splicing factors.
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miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifsThe MUC1 extracellular domain subunit is found in nuclear speckles and associates with spliceosomesU2AF-homology motif interactions are required for alternative splicing regulation by SPF45Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteinsSplicing factors SF1 and U2AF associate in extraspliceosomal complexesModulating splicing with small molecular inhibitors of the spliceosomeDimerization and protein binding specificity of the U2AF homology motif of the splicing factor Puf60Structure of Phosphorylated SF1 Bound to U2AF65 in an Essential Splicing Factor ComplexCancer-relevant Splicing Factor CAPERα Engages the Essential Splicing Factor SF3b155 in a Specific Ternary ComplexCooperative structure of the heterotrimeric pre-mRNA retention and splicing complexMicrobial and Natural Metabolites That Inhibit Splicing: A Powerful Alternative for Cancer TreatmentSF3b1 mutations associated with myelodysplastic syndromes alter the fidelity of branchsite selection in yeastIntrinsic disorder in the human spliceosomal proteome.RNA induces conformational changes in the SF1/U2AF65 splicing factor complexAnalysis of in situ pre-mRNA targets of human splicing factor SF1 reveals a function in alternative splicingPurification, crystallization and preliminary X-ray crystallographic analysis of a central domain of human splicing factor 1.Multiple aromatic side chains within a disordered structure are critical for transcription and transforming activity of EWS family oncoproteins.Solution conformation and thermodynamic characteristics of RNA binding by the splicing factor U2AF65Different requirements of the kinase and UHM domains of KIS for its nuclear localization and binding to splicing factors.Interactome for auxiliary splicing factor U2AF(65) suggests diverse roles.A homolog of splicing factor SF1 is essential for development and is involved in the alternative splicing of pre-mRNA in Arabidopsis thaliana.SF1 Phosphorylation Enhances Specific Binding to U2AF65 and Reduces Binding to 3'-Splice-Site RNA.Branch point identification and sequence requirements for intron splicing in Plasmodium falciparum.Unmasking the U2AF homology motif family: a bona fide protein-protein interaction motif in disguise.RRM domain of Arabidopsis splicing factor SF1 is important for pre-mRNA splicing of a specific set of genes.Retention and splicing complex (RES) - the importance of cooperativity.Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin ASF3B1 is a stress-sensitive splicing factor that regulates both HSF1 concentration and activity.An unusual RNA recognition motif acts as a scaffold for multiple proteins in the pre-mRNA retention and splicing complex.Promiscuity in protein-RNA interactions: conformational ensembles facilitate molecular recognition in the spliceosome: conformational diversity in U2AF⁶⁵ facilitates binding to diverse RNA sequences.
P2860
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P2860
Multiple U2AF65 binding sites within SF3b155: thermodynamic and spectroscopic characterization of protein-protein interactions among pre-mRNA splicing factors.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Multiple U2AF65 binding sites ...... ong pre-mRNA splicing factors.
@ast
Multiple U2AF65 binding sites ...... ong pre-mRNA splicing factors.
@en
type
label
Multiple U2AF65 binding sites ...... ong pre-mRNA splicing factors.
@ast
Multiple U2AF65 binding sites ...... ong pre-mRNA splicing factors.
@en
prefLabel
Multiple U2AF65 binding sites ...... ong pre-mRNA splicing factors.
@ast
Multiple U2AF65 binding sites ...... ong pre-mRNA splicing factors.
@en
P2093
P2860
P1476
Multiple U2AF65 binding sites ...... ong pre-mRNA splicing factors.
@en
P2093
Joseph M Kabogo
Karen R Thickman
Matthew C Swenson
Zygmunt Gryczynski
P2860
P304
P356
10.1016/J.JMB.2005.11.067
P407
P577
2005-12-07T00:00:00Z