Src-mediated phosphorylation of Hsp90 in response to vascular endothelial growth factor (VEGF) is required for VEGF receptor-2 signaling to endothelial NO synthase.
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Contribution of chaperones to STAT pathway signaling.Two strategies for the development of mitochondrion-targeted small molecule radiation damage mitigatorsEndothelial Cell mTOR Complex-2 Regulates Sprouting AngiogenesisLPS induces pp60c-src-mediated tyrosine phosphorylation of Hsp90 in lung vascular endothelial cells and mouse lung.The neuroendocrine-derived peptide parathyroid hormone-related protein promotes prostate cancer cell growth by stabilizing the androgen receptor.A compartment model of VEGF distribution in humans in the presence of soluble VEGF receptor-1 acting as a ligand trapMolecular regulation of tumor angiogenesis and perfusion via redox signaling.Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function.Methylnaltrexone potentiates the anti-angiogenic effects of mTOR inhibitorsCalcium/calmodulin-dependent kinase II mediates the phosphorylation and activation of NADPH oxidase 5.Deciphering mechanisms controlling placental artery endothelial cell migration stimulated by vascular endothelial growth factor.HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.A heat-shock protein axis regulates VEGFR2 proteolysis, blood vessel development and repair.Post-translational modifications of Hsp90 and their contributions to chaperone regulationN-terminal domain of soluble epoxide hydrolase negatively regulates the VEGF-mediated activation of endothelial nitric oxide synthase.Casein kinase 2 phosphorylation of Hsp90 threonine 22 modulates chaperone function and drug sensitivity.The matricellular protein thrombospondin-1 globally regulates cardiovascular function and responses to stress via CD47.Histone deacetylase inhibitors prevent pulmonary endothelial hyperpermeability and acute lung injury by regulating heat shock protein 90 function.Tumor-intrinsic and tumor-extrinsic factors impacting hsp90- targeted therapy.Broad targeting of resistance to apoptosis in cancer.Hsp90 is expressed and represents a therapeutic target in human oesophageal cancer using the inhibitor 17-allylamino-17-demethoxygeldanamycin.Hsp90, an unlikely ally in the war on cancer.Regulation of nitric oxide signalling by thrombospondin 1: implications for anti-angiogenic therapiesThe regulatory mechanism of a client kinase controlling its own release from Hsp90 chaperone machinery through phosphorylationHsp90 as a therapeutic target in patients with oesophageal carcinoma.Hsp90 as a gatekeeper of tumor angiogenesis: clinical promise and potential pitfalls.Conformational dynamics of the molecular chaperone Hsp90Lipid rafts: signaling and sorting platforms of cells and their roles in cancer.Antiangiogenic-induced hypertension: the molecular basis of signaling network.The enhanced permeability retention effect: a new paradigm for drug targeting in infection.Posttranslational modification and quality control.Regulation of molecular chaperones through post-translational modifications: decrypting the chaperone code.Contributions of co-chaperones and post-translational modifications towards Hsp90 drug sensitivity.Erythropoietin for the treatment of subarachnoid hemorrhage: A feasible ingredient for a successful medical recipe.Alternative approaches to Hsp90 modulation for the treatment of cancer.Redox regulation of gasotransmission in the vascular system: A focus on angiogenesis.Mechanisms in decorin regulation of vascular endothelial growth factor-induced human trophoblast migration and acquisition of endothelial phenotype.Role of Src in breast cancer cell migration and invasion in a breast cell/bone-derived cell microenvironment.The Molecular Basis of Portal Hypertension.The p38 pathway, a major pleiotropic cascade that transduces stress and metastatic signals in endothelial cells.
P2860
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P2860
Src-mediated phosphorylation of Hsp90 in response to vascular endothelial growth factor (VEGF) is required for VEGF receptor-2 signaling to endothelial NO synthase.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Src-mediated phosphorylation o ...... ng to endothelial NO synthase.
@ast
Src-mediated phosphorylation o ...... ng to endothelial NO synthase.
@en
type
label
Src-mediated phosphorylation o ...... ng to endothelial NO synthase.
@ast
Src-mediated phosphorylation o ...... ng to endothelial NO synthase.
@en
prefLabel
Src-mediated phosphorylation o ...... ng to endothelial NO synthase.
@ast
Src-mediated phosphorylation o ...... ng to endothelial NO synthase.
@en
P2093
P2860
P356
P1476
Src-mediated phosphorylation o ...... ing to endothelial NO synthase
@en
P2093
Fabrice Le Boeuf
Jacques Huot
Martine Duval
P2860
P304
P356
10.1091/MBC.E07-05-0467
P577
2007-09-12T00:00:00Z