Inferring synthetic lethal interactions from mutual exclusivity of genetic events in cancer. - Test2 - elhamkhani - TriplyDB

Inferring synthetic lethal interactions from mutual exclusivity of genetic events in cancer.

Inferring synthetic lethal interactions from mutual exclusivity of genetic events in cancer.

http://www.wikidata.org/entity/Q36111892

about

MicroRNA in breast cancer: The association with BRCA1/2.Synthetic lethality: emerging targets and opportunities in melanoma.Ranking novel cancer driving synthetic lethal gene pairs using TCGA data.Differential requirements for Tousled-like kinases 1 and 2 in mammalian development.Computational approaches for the identification of cancer genes and pathways DUB3 and USP7 de-ubiquitinating enzymes control replication inhibitor Geminin: molecular characterization and associations with breast cancer.Link synthetic lethality to drug sensitivity of cancer cells.Identifying mutual exclusivity across cancer genomes: computational approaches to discover genetic interaction and reveal tumor vulnerability.Synthetic Lethality-based Identification of Targets for Anticancer Drugs in the Human Signaling Network.Understanding the functional impact of copy number alterations in breast cancer using a network modeling approach

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P2860

Inferring synthetic lethal interactions from mutual exclusivity of genetic events in cancer.

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P2860

Cancer genome landscapes

The Cancer Genome Atlas Pan-Cancer analysis project

GeneCards Version 3: the human gene integrator

Comprehensive molecular portraits of human breast tumours

How many more breast cancer predisposition genes are there?

Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review

Integrated genomic analyses of ovarian carcinoma

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

The concept of synthetic lethality in the context of anticancer therapy

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