Metabolomics-Based Screening of the Malaria Box Reveals both Novel and Established Mechanisms of Action.
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Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicateMetabolomic Profiling of the Malaria Box Reveals Antimalarial Target Pathways.Novel Plasmodium falciparum metabolic network reconstruction identifies shifts associated with clinical antimalarial resistance.Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery.Review of emerging metabolomic tools and resources: 2015-2016.Plasma metabolomics reveals membrane lipids, aspartate/asparagine and nucleotide metabolism pathway differences associated with chloroquine resistance in Plasmodium vivax malariaAntimalarial activity of Malaria Box Compounds against Plasmodium falciparum clinical isolates.malERA: An updated research agenda for basic science and enabling technologies in malaria elimination and eradication.A High Parasite Density Environment Induces Transcriptional Changes and Cell Death in Plasmodium falciparum Blood Stages.Multi-omics Based Identification of Specific Biochemical Changes Associated With PfKelch13-Mutant Artemisinin-Resistant Plasmodium falciparum.Specific Inhibition of the Bifunctional Farnesyl/Geranylgeranyl Diphosphate Synthase in Malaria Parasites via a New Small-Molecule Binding Site.Targeted Phenotypic Screening in Plasmodium falciparum and Toxoplasma gondii Reveals Novel Modes of Action of Medicines for Malaria Venture Malaria Box Molecules.Influential Parameters for the Analysis of Intracellular Parasite Metabolomics.Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues.
P2860
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P2860
Metabolomics-Based Screening of the Malaria Box Reveals both Novel and Established Mechanisms of Action.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Metabolomics-Based Screening o ...... ablished Mechanisms of Action.
@ast
Metabolomics-Based Screening o ...... ablished Mechanisms of Action.
@en
type
label
Metabolomics-Based Screening o ...... ablished Mechanisms of Action.
@ast
Metabolomics-Based Screening o ...... ablished Mechanisms of Action.
@en
prefLabel
Metabolomics-Based Screening o ...... ablished Mechanisms of Action.
@ast
Metabolomics-Based Screening o ...... ablished Mechanisms of Action.
@en
P2093
P2860
P50
P356
P1476
Metabolomics-Based Screening o ...... ablished Mechanisms of Action.
@en
P2093
Benjamin K Dickerman
James I MacRae
Malcolm J McConville
Paul R Gilson
Simon A Cobbold
P2860
P304
P356
10.1128/AAC.01226-16
P407
P577
2016-08-29T00:00:00Z