p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling.
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Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formationP53 functional abnormality in mesenchymal stem cells promotes osteosarcoma developmentMolecular Aspects of Bone Resorption in β-Thalassemia MajorCell Death in Chondrocytes, Osteoblasts, and OsteocytesProtein palmitoylation regulates osteoblast differentiation through BMP-induced osterix expressionIdentification of genes for complex diseases using integrated analysis of multiple types of genomic data.Identification and characterization of microRNAs by high through-put sequencing in mesenchymal stem cells and bone tissue from mice of age-related osteoporosis.Lentiviral arrays for live-cell dynamic monitoring of gene and pathway activity during stem cell differentiation.p53 plays a role in mesenchymal differentiation programs, in a cell fate dependent mannerMouse models of p53 functions.The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice.Time series gene expression profiling and temporal regulatory pathway analysis of BMP6 induced osteoblast differentiation and mineralization.p53 at a glance.Identification of genes for complex diseases by integrating multiple types of genomic data.Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGF{beta} stimulation of RANKL productionElevated expression of Runx2 as a key parameter in the etiology of osteosarcoma.Ablation of Tak1 in osteoclast progenitor leads to defects in skeletal growth and bone remodeling in mice.Osteosarcoma in Paget's disease of bone.Microgravity induces pelvic bone loss through osteoclastic activity, osteocytic osteolysis, and osteoblastic cell cycle inhibition by CDKN1a/p21.Loss of the osteogenic differentiation potential during senescence is limited to bone progenitor cells and is dependent on p53.Gene expression profiles resulting from stable loss of p53 mirrors its role in tissue differentiation.Overexpression of the PLAP-1 gene inhibits the differentiation of BMSCs into osteoblast-like cells.p53 loss increases the osteogenic differentiation of bone marrow stromal cellsp53 in stem cellsFibulin-1 is required for bone formation and Bmp-2-mediated induction of Osterix.Modeling familial cancer with induced pluripotent stem cellsThe impact of osteoblastic differentiation on osteosarcomagenesis in the mouse.Pannexin 3 functions as an ER Ca(2+) channel, hemichannel, and gap junction to promote osteoblast differentiation.Transcriptional Profiling of Laser Capture Microdissected Subpopulations of the Osteoblast Lineage Provides Insight Into the Early Response to Sclerostin Antibody in Rats.Ascorbic acid regulates osterix expression in osteoblasts by activation of prolyl hydroxylase and ubiquitination-mediated proteosomal degradation pathwayCre-mediated recombination can induce apoptosis in vivo by activating the p53 DNA damage-induced pathwayEthanol impairs estrogen receptor signaling resulting in accelerated activation of senescence pathways, whereas estradiol attenuates the effects of ethanol in osteoblasts.Age-related BMAL1 change affects mouse bone marrow stromal cell proliferation and osteo-differentiation potential.p53 and MDM2 are involved in the regulation of osteocalcin gene expression.Signaling networks that control the lineage commitment and differentiation of bone cells.Impairment of osteoblast differentiation due to proliferation-independent telomere dysfunction in mouse models of accelerated agingAttenuation of WNT signaling by DKK-1 and -2 regulates BMP2-induced osteoblast differentiation and expression of OPG, RANKL and M-CSFSkeletons in the p53 tumor suppressor closet: genetic evidence that p53 blocks bone differentiation and developmentAdenovirus-mediated p53 tumor suppressor gene therapy of osteosarcoma.The mysterious human epidermal cell cycle, or an oncogene-induced differentiation checkpoint.
P2860
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P2860
p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
p53 functions as a negative re ...... ogenesis, and bone remodeling.
@ast
p53 functions as a negative re ...... ogenesis, and bone remodeling.
@en
type
label
p53 functions as a negative re ...... ogenesis, and bone remodeling.
@ast
p53 functions as a negative re ...... ogenesis, and bone remodeling.
@en
prefLabel
p53 functions as a negative re ...... ogenesis, and bone remodeling.
@ast
p53 functions as a negative re ...... ogenesis, and bone remodeling.
@en
P2093
P2860
P356
P1476
p53 functions as a negative re ...... ogenesis, and bone remodeling.
@en
P2093
Benoit de Crombrugghe
Gerard Karsenty
Hui-Yi Kua
Xueying Wang
P2860
P304
P356
10.1083/JCB.200507106
P407
P50
P577
2005-12-27T00:00:00Z