Direct pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonist

Direct pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonist

Item
http://www.wikidata.org/entity/Q36158931
NMDA receptor modulators: an updated patent review (2013-2014)The Concise Guide to PHARMACOLOGY 2013/14: ligand-gated ion channels.Functional assessment of the NMDA receptor variant GluN2A R586K.NMDA receptors control vagal afferent excitability in the nucleus of the solitary tract.Subunit-selective allosteric inhibition of glycine binding to NMDA receptorsTCN 201 selectively blocks GluN2A-containing NMDARs in a GluN1 co-agonist dependent but non-competitive mannerContribution of the M1 transmembrane helix and pre-M1 region to positive allosteric modulation and gating of N-methyl-D-aspartate receptorsInfluence of GluN2 subunit identity on NMDA receptor function.GluN2D-Containing N-methyl-d-Aspartate Receptors Mediate Synaptic Transmission in Hippocampal Interneurons and Regulate Interneuron Activity.NMDA Receptors in the Central Nervous System.Synthesis, radio-synthesis and in vitro evaluation of terminally fluorinated derivatives of HU-210 and HU-211 as novel candidate PET tracers.Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons.Disease-associated missense mutations in GluN2B subunit alter NMDA receptor ligand binding and ion channel properties.
P2860

Direct pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonist

Item
http://www.wikidata.org/entity/Q36158931
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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2012年论文
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2012年论文
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name
Direct pharmacological monitor ...... , glycine-dependent antagonist
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Direct pharmacological monitor ...... , glycine-dependent antagonist
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type
label
Direct pharmacological monitor ...... , glycine-dependent antagonist
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Direct pharmacological monitor ...... , glycine-dependent antagonist
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Direct pharmacological monitor ...... , glycine-dependent antagonist
@ast
Direct pharmacological monitor ...... , glycine-dependent antagonist
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Direct pharmacological monitor ...... , glycine-dependent antagonist
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10.1111/J.1476-5381.2011.01748.X
P407
P433
P478
P50
P577
P5875
P698
P932