The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability.
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Genome-wide array comparative genomic hybridization analysis reveals distinct amplifications in osteosarcomaOsteosarcoma: Cells-of-Origin, Cancer Stem Cells, and Targeted TherapiesMicroRNAs and Potential Targets in Osteosarcoma: ReviewLinks between mutant p53 and genomic instabilityFOXM1 in sarcoma: role in cell cycle, pluripotency genes and stem cell pathwaysAltered expression and deletion of RMO1 in osteosarcomaNew small molecules targeting apoptosis and cell viability in osteosarcomaMicroarray and ChIP-seq data analysis revealed changes in p53-mediated transcriptional regulation in Nutlin-3-treated U2OS cellsExomic analysis of myxoid liposarcomas, synovial sarcomas, and osteosarcomasOsteosarcoma Overview.Cis lethal genetic interactions attenuate and alter p53 tumorigenesis.The expression and significance of IDH1 and p53 in osteosarcomaAnimal models in osteosarcoma.TP53 mutational status is a potential marker for risk stratification in Wilms tumour with diffuse anaplasia.Cell cycle regulator gene CDC5L, a potential target for 6p12-p21 amplicon in osteosarcomaThe genetics of osteosarcoma.A new approach for prediction of tumor sensitivity to targeted drugs based on functional dataMMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression.Lack of major genome instability in tumors of p53 null ratsWhole exome sequencing of a single osteosarcoma case--integrative analysis with whole transcriptome RNA-seq data.Identification of transcriptional factors and key genes in primary osteoporosis by DNA microarray.Gain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expressionAn Old Story Retold: Loss of G1 Control Defines A Distinct Genomic Subtype of Esophageal Squamous Cell CarcinomaTranscriptional Profiling Identifies the Signaling Axes of IGF and Transforming Growth Factor-b as Involved in the Pathogenesis of OsteosarcomaInitial testing of the MDM2 inhibitor RG7112 by the Pediatric Preclinical Testing ProgramNovel siRNA formulation to effectively knockdown mutant p53 in osteosarcomaGenetically engineered mouse models and human osteosarcoma.Adenovirus-mediated p53 tumor suppressor gene therapy of osteosarcoma.A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis.Array-based comparative genomic hybridization for genomic-wide screening of DNA copy number alterations in aggressive bone tumors.Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells.A porcine model of osteosarcoma.The molecular landscape of extraskeletal osteosarcoma: A clinicopathological and molecular biomarker study.Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrationsMammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes.Osteosarcoma: mouse models, cell of origin and cancer stem cellCorrelation of transcription of MALAT-1, a novel noncoding RNA, with deregulated expression of tumor suppressor p53 in small DNA tumor virus modelsParathyroid hormone/parathyroid hormone-related peptide regulate osteosarcoma cell functions: Focus on the extracellular matrix (Review).Modulation of the E2F1-driven cancer cell fate by the DNA damage response machinery and potential novel E2F1 targets in osteosarcomasAnalysis of the molecular mechanism of osteosarcoma using a bioinformatics approach.
P2860
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P2860
The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
The presence of p53 mutations ...... levels of genomic instability.
@ast
The presence of p53 mutations ...... levels of genomic instability.
@en
type
label
The presence of p53 mutations ...... levels of genomic instability.
@ast
The presence of p53 mutations ...... levels of genomic instability.
@en
prefLabel
The presence of p53 mutations ...... levels of genomic instability.
@ast
The presence of p53 mutations ...... levels of genomic instability.
@en
P2093
P2860
P356
P1476
The presence of p53 mutations ...... levels of genomic instability.
@en
P2093
Arnold J Levine
Francis Barany
Michael B Elowitz
Michael Overholtzer
Pulivarthi H Rao
Reyna Favis
Richard Gorlick
Xin-Yan Lu
P2860
P304
11547-11552
P356
10.1073/PNAS.1934852100
P407
P50
P577
2003-09-12T00:00:00Z