Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylation
about
Replication-Associated Recombinational Repair: Lessons from Budding YeastFunctions of Ubiquitin and SUMO in DNA Replication and Replication StressMechanisms and regulation of mitotic recombination in Saccharomyces cerevisiaeRemodeling of the Rad51 DNA strand-exchange protein by the Srs2 helicase.Srs2 mediates PCNA-SUMO-dependent inhibition of DNA repair synthesis.Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates.SUMO-mediated regulation of DNA damage repair and responsesGenetic instability in budding and fission yeast-sources and mechanismsThe PCNA interaction protein box sequence in Rad54 is an integral part of its ATPase domain and is required for efficient DNA repair and recombinationDifferential requirement of Srs2 helicase and Rad51 displacement activities in replication of hairpin-forming CAG/CTG repeats.SUMO Wrestles with RecombinationUnwinding of synthetic replication and recombination substrates by Srs2.Genome maintenance in Saccharomyces cerevisiae: the role of SUMO and SUMO-targeted ubiquitin ligases.Srs2 and Mus81-Mms4 Prevent Accumulation of Toxic Inter-Homolog Recombination Intermediates.Local regulation of the Srs2 helicase by the SUMO-like domain protein Esc2 promotes recombination at sites of stalled replication.Pro-recombination Role of Srs2 Protein Requires SUMO (Small Ubiquitin-like Modifier) but Is Independent of PCNA (Proliferating Cell Nuclear Antigen) Interaction.SUMOylation of the farnesoid X receptor (FXR) regulates the expression of FXR target genes.Lif1 SUMOylation and its role in non-homologous end-joining.SUMOylation of Rad52-Rad59 synergistically change the outcome of mitotic recombination.Unloading of homologous recombination factors is required for restoring double-stranded DNA at damage repair loci.Sumoylation and the DNA damage responseSumo and the cellular stress response.Multifunctional roles of Saccharomyces cerevisiae Srs2 protein in replication, recombination and repair.Functions of SUMO in the Maintenance of Genome Stability.A genetic screen for high copy number suppressors of the synthetic lethality between elg1Δ and srs2Δ in yeast.The SUMO deconjugating peptidase Smt4 contributes to the mechanism required for transition from sister chromatid arm cohesion to sister chromatid pericentromere separation.Building up and breaking down: mechanisms controlling recombination during replication.DNA Damage Tolerance Pathway Choice Through Uls1 Modulation of Srs2 SUMOylation in Saccharomyces cerevisiae.Tight Regulation of Srs2 Helicase Activity Is Crucial for Proper Functioning of DNA Repair Mechanisms.A crucial role of SUMOylation in modulating Sirt6 deacetylation of H3 at lysine 56 and its tumor suppressive activity.The Main Role of Srs2 in DNA Repair Depends on Its Helicase Activity, Rather than on Its Interactions with PCNA or Rad51Binding properties of SUMO-interacting motifs (SIMs) in yeastUbiquitylation at the Fork: Making and Breaking Chains to Complete DNA Replication
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P2860
Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylation
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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2012年论文
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name
Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylation
@ast
Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylation
@en
type
label
Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylation
@ast
Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylation
@en
prefLabel
Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylation
@ast
Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylation
@en
P2860
P50
P356
P1476
Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylation
@en
P2093
Prabha Sarangi
Veronika Altmannova
P2860
P304
P356
10.1093/NAR/GKS484
P407
P577
2012-06-16T00:00:00Z