Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors. - Test2 - elhamkhani - TriplyDB

Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors.

Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors.

http://www.wikidata.org/entity/Q36239602

about

A novel human DNA-binding protein with sequence similarity to a subfamily of redox proteins which is able to repress RNA-polymerase-III-driven transcription of the Alu-family retroposons in vitro Histone deacetylase 7 associates with Runx2 and represses its activity during osteoblast maturation in a deacetylation-independent manner Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory element RGS12TS-S localizes at nuclear matrix-associated subnuclear structures and represses transcription: structural requirements for subnuclear targeting and transcriptional repression.Sp2 localizes to subnuclear foci associated with the nuclear matrix Live cell imaging of the cancer-related transcription factor RUNX2 during mitotic progression The inv(16) encodes an acute myeloid leukemia 1 transcriptional corepressor Matrin3: connecting gene expression with the nuclear matrix Multiple levels of epigenetic control for bone biology and pathology A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia Nuclear import and subnuclear localization of the proto-oncoprotein ETO (MTG8)A-kinase-anchoring protein AKAP95 is targeted to the nuclear matrix and associates with p68 RNA helicase The newly identified human nuclear protein NXP-2 possesses three distinct domains, the nuclear matrix-binding, RNA-binding, and coiled-coil domains Dynamic in vivo interactions among Myc network members Identification of a common subnuclear localization signal The RUNX genes: gain or loss of function in cancer Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells Mitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cells Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter Human umbilical cord blood-derived CD34+ cells reverse osteoporosis in NOD/SCID mice by altering osteoblastic and osteoclastic activities Protein localization with flexible DNA or RNA.Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: biology and clinical significance.Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.Point mutation in AML1 disrupts subnuclear targeting, prevents myeloid differentiation, and effects a transformation-like phenotype.Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer.Subnuclear targeting of the Runx3 tumor suppressor and its epigenetic association with mitotic chromosomes.Distinct contributions of conserved modules to Runt transcription factor activity Multiple Cbfa/AML sites in the rat osteocalcin promoter are required for basal and vitamin D-responsive transcription and contribute to chromatin organization.runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins.Bone tissue specific transcriptional control: options for targeting gene therapy to the skeleton.The leukemogenic t(8;21) fusion protein AML1-ETO controls rRNA genes and associates with nucleolar-organizing regions at mitotic chromosomes.Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites.Variant-type PML-RAR(alpha) fusion transcript in acute promyelocytic leukemia: use of a cryptic coding sequence from intron 2 of the RAR(alpha) gene and identification of a new clinical subtype resistant to retinoic acid therapy.The dynamic organization of gene-regulatory machinery in nuclear microenvironments Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network.Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins.AML1 and the AML1-ETO fusion protein in the pathogenesis of t(8;21) AML.

P2860

Q22009106-1349170D-95E7-4106-A695-4EA0C5D29D19 Q24300259-4A6E4F66-2897-4659-9A3D-3E003E504BEB Q24316983-EF49A3AB-6583-4015-87D2-2F6752447E70 Q24336420-DA45B15C-717F-4227-805F-1AAF933C29DE Q24537435-0A93EDA3-8B17-4B08-8060-783A403CAD31 Q24541557-9EF774F6-9629-4DF2-AD22-F940F505091E Q24606439-9A2126DE-3588-49CA-8709-A02F38767D46 Q24650487-71FE5171-A3D6-4288-94B3-A04AF9F7BC01 Q26774243-E39635B0-A404-40A9-955E-9C4DA8DF8AFB Q28083715-20B8B56E-F9C1-497A-99C2-75285EA1665E Q28141676-877EB72B-BF2F-4C63-9A7C-CEB38007A5C0 Q28144264-1BA5F2F5-0686-48A2-BCAE-8A28389CA73C Q28208881-A7BF87BA-7271-46E8-A76B-0F0A8E6C859B Q28212070-12144BD5-EBC8-4451-9D99-83FC74BB835D Q28212240-26140CC7-03B0-4CB5-A42F-BD899178CEF2 Q28237633-C7584430-62C8-461F-B6D1-C27B4EEDF2DD Q28247901-1A4227AF-E536-483C-9CD5-2A57F4DD55E3 Q28506055-95AF5960-2A64-4CC6-A731-9DBF4BD6AE4F Q28565698-C27AD884-FB90-48C9-A329-E2F3A8FE3A76 Q28573678-73D12579-1727-4A2C-A5A7-8BC0B09A1B15 Q28593503-773C9E2B-9207-4E7F-80A3-BDD578D42F2B Q28728315-F8296716-8976-422F-9C54-BA6821DC0600 Q31048871-7437FE5B-B84A-4F03-AB7B-A9E6B09E41D0 Q33697682-2E33AA26-CEC6-428B-A3EB-B500862BAC6A Q33719096-0B12BDD9-CE88-495C-9280-66258C6CE4C6 Q33819359-A86571E4-8286-4A5A-A6C0-94353DA08D68 Q33821606-942B3CA8-DFD6-47ED-8513-50AC6D112720 Q33823421-C6DFAD69-F01C-4F96-B9E8-A784C76D5417 Q33917511-6A42FE13-61E1-4825-A530-E2B94A9EE126 Q33948578-227435C3-1EC4-4EFF-B38E-4ED97D7F6893 Q33960022-06FF6CA3-3485-4949-ABCB-50879BF39BC7 Q33967954-8A413FBB-E712-49DE-85A0-7F0AEE4514B8 Q33970455-0866FD0C-265F-446E-97E5-4CD24CBE76C3 Q33995514-0CBEA765-0FA3-4158-A25E-EB9BF8701650 Q34031066-877A9295-1428-44AC-9B43-D1722507EDF2 Q34064907-4B8C800E-5861-42AE-9CBE-FD55AA8C1862 Q34166634-9D70970D-0ED6-45F1-BAB8-5AFCDB5CCE80 Q34372000-FDAA419B-FF65-43D5-B2C1-B22276950CA3 Q34386755-38AFF657-E1B8-45F4-A882-642CAFCA4BA6 Q34405452-466198D5-A9BC-4A94-85A5-E663044CD6F1

P2860

Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors.

http://www.wikidata.org/entity/Q36239602

description

1997 nî lūn-bûn

@nan

1997年の論文

@ja

1997年論文

@yue

1997年論文

@zh-hant

1997年論文

@zh-hk

1997年論文

@zh-mo

1997年論文

@zh-tw

1997年论文

@wuu

1997年论文

@zh

1997年论文

@zh-cn

name

Identification of a nuclear ma ...... F-alpha transcription factors.

@ast

Identification of a nuclear ma ...... F-alpha transcription factors.

@en

type

label

Identification of a nuclear ma ...... F-alpha transcription factors.

@ast

Identification of a nuclear ma ...... F-alpha transcription factors.

@en

prefLabel

Identification of a nuclear ma ...... F-alpha transcription factors.

@ast

Identification of a nuclear ma ...... F-alpha transcription factors.

@en

P1433

Q36239602-464ABBDD-6C8F-4DB3-8AA2-5C9D6254FBE9

P1476

Q36239602-7E421B30-C23D-4B65-B2D6-67486383AAC1

P2093

Q36239602-0F1DB386-F02F-4966-8745-6F65E837E140

Q36239602-1930AEE6-26F1-42CE-89D8-7EC8624C320D

Q36239602-2B5FB9BC-28A8-4F61-BCC2-40DAF1577C3B

Q36239602-3EE340CB-1C84-48F0-8D72-E2324C2408F8

Q36239602-3F6D3163-C2AB-44EF-976A-2BF43560F4AA

Q36239602-51324992-9616-4A76-9C50-551B68FB1DC1

Q36239602-5E997CCD-8E8C-4BCC-BB0A-F7760D3918DC

Q36239602-7375D5FC-46A1-4B48-9FE7-E8F088EFABE4

Q36239602-779BE790-F81E-416C-9309-2F9973801944

Q36239602-D9D5E515-31DF-4EF3-97C4-B329FF9F5AEC

P2860

Q36239602-00DFB41C-F81A-4ABB-959E-DCFE74A8E41E

Q36239602-02D966CF-8789-4BC8-91B2-E27132E1BCA8

Q36239602-0CE10CD5-DD70-414F-A443-E24455A2DACD

Q36239602-12D6FC3D-8706-4B17-90F8-EA8A570BDE4D

Q36239602-153D379A-489F-44D7-AAFD-061B4086331B

Q36239602-15E45FC6-7661-4640-8CEC-66BBD9D9C080

Q36239602-1704A44A-1C69-4B19-B0A2-33E4A89C803C

Q36239602-182B2F82-F93A-4A7E-B327-2647DD744334

Q36239602-18626032-D0CF-4A14-AD0E-3EC90D9EECEA

Q36239602-19D2E013-149F-494A-AC0C-38F4D8CBBC0E

P304

Q36239602-904EDBF7-F5BE-4BA2-B7ED-E6FD3AF8AD23

P31

Q36239602-4DDA42AA-52AA-47AB-A1EB-FB3295A13758

P356

Q36239602-0915F820-3C31-4170-A372-A490EBAAB5F4

P407

Q36239602-D09A0CD4-EF01-4ECB-900A-5D90F2D1EE3A

P433

Q36239602-960C9227-5B8A-4F92-A873-5A5EE62DF184

P478

Q36239602-2272EA7A-9823-4623-80BA-755CC54AA54A

P577

Q36239602-BAB9E9E7-C0B5-4DEC-BC55-DB0241D280AB

P5875

Q36239602-177F63CA-6CD0-48C9-A06F-9693C1D87085

P698

Q36239602-33150BBF-C5DD-4FA0-B0A0-B404B71B8416

P932

Q36239602-EE93BE7F-58A7-412D-B7A5-759B1715DCAC

P356

PNAS.94.13.6746

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Identification of a nuclear ma ...... F-alpha transcription factors.

@en

P2093

A J van Wijnen

http://www.w3.org/2001/XMLSchema#string

C Zeng

http://www.w3.org/2001/XMLSchema#string

G S Stein

http://www.w3.org/2001/XMLSchema#string

J B Lawrence

http://www.w3.org/2001/XMLSchema#string

J B Lian

http://www.w3.org/2001/XMLSchema#string

J L Stein

http://www.w3.org/2001/XMLSchema#string

L Shopland

http://www.w3.org/2001/XMLSchema#string

S Meyers

http://www.w3.org/2001/XMLSchema#string

S Penman

http://www.w3.org/2001/XMLSchema#string

S W Hiebert

http://www.w3.org/2001/XMLSchema#string

P2860

AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization

Subcellular localization of the alpha and beta subunits of the acute myeloid leukemia-linked transcription factor PEBP2/CBF

Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

A tissue-specific MAR/SAR DNA-binding protein with unusual binding site recognition

The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript

Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia

Alternative splicing and genomic structure of the AML1 gene involved in acute myeloid leukemia

XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure

Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization

P304

6746-6751

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.94.13.6746

http://www.w3.org/2001/XMLSchema#string

P407

P433

13

http://www.w3.org/2001/XMLSchema#string

P478

94

http://www.w3.org/2001/XMLSchema#string

P577

1997-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

235617330

http://www.w3.org/2001/XMLSchema#string

P698

9192636

http://www.w3.org/2001/XMLSchema#string

P932

21229

http://www.w3.org/2001/XMLSchema#string