Wnt addiction of genetically defined cancers reversed by PORCN inhibition. - Test2 - elhamkhani - TriplyDB

Wnt addiction of genetically defined cancers reversed by PORCN inhibition.

Wnt addiction of genetically defined cancers reversed by PORCN inhibition.

http://www.wikidata.org/entity/Q36292664

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Promising Druggable Target in Head and Neck Squamous Cell Carcinoma: Wnt Signaling Wnt Signaling in Cancer Stem Cell Biology Control of Wnt Receptor Turnover by R-spondin-ZNRF3/RNF43 Signaling Module and Its Dysregulation in Cancer Bridging academic science and clinical research in the search for novel targeted anti-cancer agents Fatty acylation of proteins: The long and the short of it.Diversity of Precursor Lesions For Pancreatic Cancer: The Genetics and Biology of Intraductal Papillary Mucinous Neoplasm R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine Physiologically relevant human tissue models for infectious diseases.USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds.NOTUM is a potential pharmacodynamic biomarker of Wnt pathway inhibition.Novel targeted therapies in adrenocortical carcinoma.Loss of AXIN1 drives acquired resistance to WNT pathway blockade in colorectal cancer cells carrying RSPO3 fusions The Wnt signaling pathway in cancer.Winding back Wnt signalling: potential therapeutic targets for treating gastric cancers.A Wntless-SEC12 complex on the ER membrane regulates early Wnt secretory vesicle assembly and mature ligand export.From tumour heterogeneity to advances in precision treatment of colorectal cancer.Novel therapeutics in metastatic colorectal cancer: molecular insights and pharmacogenomic implications.Challenging chemoresistant metastatic colorectal cancer: therapeutic strategies from the clinic and from the laboratory.Modulating the wnt signaling pathway with small molecules.The Contributions of Human Mini-Intestines to the Study of Intestinal Physiology and Pathophysiology.Wnt Signaling and Colorectal Cancer.Pharmacological interventions in the Wnt pathway: inhibition of Wnt secretion versus disrupting the protein-protein interfaces of nuclear factors.Targeting the Wnt Pathway in Cancer: A Review of Novel Therapeutics.Delivery of the Porcupine Inhibitor WNT974 in Mice.Wnt signalling pathways in chronic lymphocytic leukaemia and B-cell lymphomas.Molecular genetics and targeted therapy of WNT-related human diseases (Review).Wnt is necessary for mesenchymal to epithelial transition in colorectal cancer cells.Recent developments in the treatment of metastatic colorectal cancer.Discovery of Pyridinyl Acetamide Derivatives as Potent, Selective, and Orally Bioavailable Porcupine Inhibitors.Canonical and non-canonical WNT signaling in cancer stem cells and their niches: Cellular heterogeneity, omics reprogramming, targeted therapy and tumor plasticity (Review)Pharmacologic Manipulation of Wnt Signaling and Cancer Stem Cells.Development of a triazole class of highly potent Porcn inhibitors.Functions of the APC tumor suppressor protein dependent and independent of canonical WNT signaling: implications for therapeutic targeting.Enhanced targeting of CML stem and progenitor cells by inhibition of porcupine acyltransferase in combination with TKI.DDB2 Is a Novel Regulator of Wnt Signaling in Colon Cancer.Advances in Molecular Profiling and Categorisation of Pancreatic Adenocarcinoma and the Implications for Therapy.WNT signalling in prostate cancer.Comprehensive characterization of RSPO fusions in colorectal traditional serrated adenomas.Wnt disruption in colorectal polyps - the traditional serrated adenoma enters the fray.Wnt signaling in cancer.

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Wnt addiction of genetically defined cancers reversed by PORCN inhibition.

http://www.wikidata.org/entity/Q36292664

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2015 nî lūn-bûn

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2015年学术文章

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2015年學術文章

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2015年學術文章

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2015年學術文章

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Wnt addiction of genetically defined cancers reversed by PORCN inhibition.

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Wnt addiction of genetically defined cancers reversed by PORCN inhibition.

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Wnt addiction of genetically defined cancers reversed by PORCN inhibition.

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Wnt addiction of genetically defined cancers reversed by PORCN inhibition.

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Wnt addiction of genetically defined cancers reversed by PORCN inhibition.

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Wnt addiction of genetically defined cancers reversed by PORCN inhibition.

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P2860

Differential expression analysis for sequence count data

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

Structural basis of Wnt recognition by Frizzled

c-Myc-regulated microRNAs modulate E2F1 expression

Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation

TRANSFAC: transcriptional regulation, from patterns to profiles

HTSeq--a Python framework to work with high-throughput sequencing data

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