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Bivalent binding drives the formation of the Grb2-Gab1 signaling complex in a noncooperative mannerCa(2+) transfer from the ER to mitochondria: when, how and whyMolecular pathways: targeting phosphoinositide 3-kinase p110-delta in chronic lymphocytic leukemiaNitrosylcobalamin potentiates the anti-neoplastic effects of chemotherapeutic agents via suppression of survival signalingmiR-200c sensitizes breast cancer cells to doxorubicin treatment by decreasing TrkB and Bmi1 expressionA urokinase-type plasminogen activator deficiency diminishes the frequency of intestinal adenomas in ApcMin/+ miceThe pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival signalling.Allostery mediates ligand binding to Grb2 adaptor in a mutually exclusive manner.The carboxyl-terminal SH3 domain of the mammalian adaptor CrkII promotes internalization of Listeria monocytogenes through activation of host phosphoinositide 3-kinase.A comparative evaluation of ultrasound molecular imaging, perfusion imaging, and volume measurements in evaluating response to therapy in patient-derived xenograftsDysregulation of WNT/CTNNB1 and PI3K/AKT signaling in testicular stromal cells causes granulosa cell tumor of the testisPathways to tamoxifen resistance.532 nm low-power laser irradiation recovers γ-secretase inhibitor-mediated cell growth suppression and promotes cell proliferation via Akt signaling.The anti-inflammatory effect of A3 adenosine receptor agonists: a novel targeted therapy for rheumatoid arthritis.Extracting gene networks for low-dose radiation using graph theoretical algorithmsAssembly of the Sos1-Grb2-Gab1 ternary signaling complex is under allosteric controlWhole genome siRNA cell-based screen links mitochondria to Akt signaling network through uncoupling of electron transport chainAkt pathway is hypoactivated by synergistic actions of diabetes mellitus and hypercholesterolemia resulting in advanced coronary artery disease.Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinaseClinical significance of pharmacogenomic studies in tardive dyskinesia associated with patients with psychiatric disordersBinding of the cSH3 domain of Grb2 adaptor to two distinct RXXK motifs within Gab1 docker employs differential mechanisms.The emphysematous lung is abnormally sensitive to TRAIL-mediated apoptosis.Identification of components of the host type IA phosphoinositide 3-kinase pathway that promote internalization of Listeria monocytogenes.Multivalent binding and facilitated diffusion account for the formation of the Grb2-Sos1 signaling complex in a cooperative manner.Effect of specific activation of γ-aminobutyric acid receptor in vivo on oxidative stress-induced damage after extended hepatectomy.Thalidomide induces limb anomalies by PTEN stabilization, Akt suppression, and stimulation of caspase-dependent cell deathSynergistic effects of Pten loss and WNT/CTNNB1 signaling pathway activation in ovarian granulosa cell tumor development and progression.Telmisartan-induced inhibition of vascular cell proliferation beyond angiotensin receptor blockade and peroxisome proliferator-activated receptor-gamma activation.Pretreatment of Small-for-Size Grafts In Vivo by γ -Aminobutyric Acid Receptor Regulation against Oxidative Stress-Induced Injury in Rat Split Orthotopic Liver TransplantationMerkel cell carcinoma: molecular pathogenesis, clinical features and therapy.Decreased fructose-1,6-bisphosphatase-2 expression promotes glycolysis and growth in gastric cancer cells.Milk fat globule protein epidermal growth factor-8: a pivotal relay element within the angiotensin II and monocyte chemoattractant protein-1 signaling cascade mediating vascular smooth muscle cells invasion.Liver graft pretreated in vivo or ex vivo by γ-aminobutyric acid receptor regulation.Pretreatment of liver grafts in vivo by γ-aminobutyric acid receptor regulation reduces cold ischemia/warm reperfusion injury in rat.Mammalian target of rapamycin complex 2 (mTORC2) coordinates pulmonary artery smooth muscle cell metabolism, proliferation, and survival in pulmonary arterial hypertension.Melatonin as a neuroprotective agent in the rodent models of Parkinson's disease: is it all set to irrefutable clinical translation?CSF-1 signaling in macrophages: pleiotrophy through phosphotyrosine-based signaling pathways.Overcoming endocrine resistance in breast cancer: importance of mTOR inhibition.Chemical constituents of the Annona glabra fruit and their cytotoxic activity.Activation of protein kinase CK2 attenuates FOXO3a functioning in a PML-dependent manner: implications in human prostate cancer.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Akt: versatile mediator of cell survival and beyond.
@ast
Akt: versatile mediator of cell survival and beyond.
@en
type
label
Akt: versatile mediator of cell survival and beyond.
@ast
Akt: versatile mediator of cell survival and beyond.
@en
prefLabel
Akt: versatile mediator of cell survival and beyond.
@ast
Akt: versatile mediator of cell survival and beyond.
@en
P1433
P1476
Akt: versatile mediator of cell survival and beyond.
@en
P2093
Dohoon Kim
Jongkyeong Chung
P304
P356
10.5483/BMBREP.2002.35.1.106
P577
2002-01-01T00:00:00Z