Chemical approaches to targeted protein degradation through modulation of the ubiquitin-proteasome pathway
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E3 Ubiquitin Ligases Neurobiological Mechanisms: Development to DegenerationImpact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds.Synthetic Gene Expression Circuits for Designing Precision Tools in Oncology.Significance of the E3 ubiquitin protein UBR5 as an oncogene and a prognostic biomarker in colorectal cancer.Unveiling kaposi sarcoma viral antigens.Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766).A dystroglycan mutation (p.Cys667Phe) associated to muscle-eye-brain disease with multicystic leucodystrophy results in ER-retention of the mutant protein.Synthetic Gene Expression Circuits for Designing Precision Tools in Oncology.Dihydroartemisinin selectively inhibits PDGFRα-positive ovarian cancer growth and metastasis through inducing degradation of PDGFRα protein.Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways.
P2860
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P2860
Chemical approaches to targeted protein degradation through modulation of the ubiquitin-proteasome pathway
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2017 nî lūn-bûn
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2017年の論文
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2017年学术文章
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2017年学术文章
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name
Chemical approaches to targete ...... e ubiquitin-proteasome pathway
@ast
Chemical approaches to targete ...... e ubiquitin-proteasome pathway
@en
type
label
Chemical approaches to targete ...... e ubiquitin-proteasome pathway
@ast
Chemical approaches to targete ...... e ubiquitin-proteasome pathway
@en
prefLabel
Chemical approaches to targete ...... e ubiquitin-proteasome pathway
@ast
Chemical approaches to targete ...... e ubiquitin-proteasome pathway
@en
P2093
P2860
P921
P356
P1433
P1476
Chemical approaches to targete ...... e ubiquitin-proteasome pathway
@en
P2093
Hannah Wang
Ian Collins
John J Caldwell
Raj Chopra
P2860
P304
P356
10.1042/BCJ20160762
P407
P577
2017-03-15T00:00:00Z