G9a is essential for epigenetic silencing of K(+) channel genes in acute-to-chronic pain transition.
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G9A performs important roles in the progression of breast cancer through upregulating its targets.MicroRNA cluster miR-17-92 regulates multiple functionally related voltage-gated potassium channels in chronic neuropathic pain.Nerve Injury Diminishes Opioid Analgesia through Lysine Methyltransferase-mediated Transcriptional Repression of μ-Opioid Receptors in Primary Sensory Neurons.The CRISPR/Cas9 system for gene editing and its potential application in pain researchDopaminergic inhibition by G9a/Glp complex on tyrosine hydroxylase in nerve injury-induced hypersensitivityCD8+ T Cells and Endogenous IL-10 Are Required for Resolution of Chemotherapy-Induced Neuropathic Pain.G9a participates in nerve injury-induced Kcna2 downregulation in primary sensory neurons.G9a inhibits CREB-triggered expression of mu opioid receptor in primary sensory neurons following peripheral nerve injury.Recent advances in understanding neuropathic pain: glia, sex differences, and epigenetics.DNA methyltransferase DNMT3a contributes to neuropathic pain by repressing Kcna2 in primary afferent neurons.M-type K(+) channels in peripheral nociceptive pathways.Targeting Epigenetic Mechanisms for Chronic Pain: A Valid Approach for the Development of Novel Therapeutics.Drugging the pain epigenome.Breaking barriers to novel analgesic drug development.[EXPRESS] Threshold Effect of G9a/Glp on Peripheral Nerve Injury Induced Hypersensitivity.Contribution of the Suppressor of Variegation 3-9 Homolog 1 in Dorsal Root Ganglia and Spinal Cord Dorsal Horn to Nerve Injury-induced Nociceptive HypersensitivityThe transcription factor C/EBPβ in the dorsal root ganglion contributes to peripheral nerve trauma-induced nociceptive hypersensitivity.From Mechanism to Cure: Renewing the Goal to Eliminate the Disease of Pain.Postoperative pain-from mechanisms to treatment.Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain.5-Hydroxymethylcytosine (5hmC) and Ten-eleven translocation 1-3 (TET1-3) proteins in the dorsal root ganglia of mouse: Expression and dynamic regulation in neuropathic pain.Inhibition of G9a/GLP Complex Promotes Long-Term Potentiation and Synaptic Tagging/Capture in Hippocampal CA1 Pyramidal Neurons.Bortezomib induces neuropathic pain through protein kinase C-mediated activation of presynaptic NMDA receptors in the spinal cord.Signatures of Altered Gene Expression in Dorsal Root Ganglia of a Fabry Disease Mouse Model.The Dorsal Root Ganglion in the Pathogenesis of Chronic Neuropathic Pain.Macrophage migration inhibitory factor mediates peripheral nerve injury-induced hypersensitivity by curbing dopaminergic descending inhibition.The α2δ-1-NMDA Receptor Complex Is Critically Involved in Neuropathic Pain Development and Gabapentin Therapeutic Actions.EZH2 regulates spinal neuroinflammation in rats with neuropathic pain.Spinal SET7/9 may contribute to the maintenance of cancer-induced bone pain in mice.Epigenetic Modifications Associated to Neuroinflammation and Neuropathic Pain After Neural Trauma.A medial prefrontal cortex-nucleus acumens corticotropin-releasing factor circuitry for neuropathic pain-increased susceptibility to opioid reward.Negative Evidence for a Functional Role of Neuronal DNMT3a in Persistent PainHistone deacetylase inhibitors prevent persistent hypersensitivity in an orofacial neuropathic pain model
P2860
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P2860
G9a is essential for epigenetic silencing of K(+) channel genes in acute-to-chronic pain transition.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
@zh-hans
2015年学术文章
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2015年学术文章
@zh-sg
2015年學術文章
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2015年學術文章
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2015年學術文章
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name
G9a is essential for epigeneti ...... te-to-chronic pain transition.
@ast
G9a is essential for epigeneti ...... te-to-chronic pain transition.
@en
type
label
G9a is essential for epigeneti ...... te-to-chronic pain transition.
@ast
G9a is essential for epigeneti ...... te-to-chronic pain transition.
@en
prefLabel
G9a is essential for epigeneti ...... te-to-chronic pain transition.
@ast
G9a is essential for epigeneti ...... te-to-chronic pain transition.
@en
P2093
P2860
P356
P1433
P1476
G9a is essential for epigeneti ...... ute-to-chronic pain transition
@en
P2093
Geoffroy Laumet
Hui-Lin Pan
Jaroslav Jelinek
Judit Garriga
Matteo Cesaroni
Shao-Rui Chen
Yingchun Dong
Yuhao Zhang
P2860
P2888
P304
P356
10.1038/NN.4165
P407
P577
2015-11-09T00:00:00Z