Inactivating all three rb family pocket proteins is insufficient to initiate cervical cancer.
about
Cdc6 contributes to abrogating the G1 checkpoint under hypoxic conditions in HPV E7 expressing cells.High incidence of HPV-associated head and neck cancers in FA deficient mice is associated with E7's induction of DNA damage through its inactivation of pocket proteinsHPV18 E7 induces the over-transcription of eIF4E gene in cervical cancerThe papillomavirus E7 proteins.High-Risk Human Papillomavirus E7 Proteins Target PTPN14 for Degradation.Progesterone signaling inhibits cervical carcinogenesis in miceRequirement of estrogen receptor alpha DNA-binding domain for HPV oncogene-induced cervical carcinogenesis in mice.Validation of an HPV16-mediated carcinogenesis mouse model.High incidence of female reproductive tract cancers in FA-deficient HPV16-transgenic mice correlates with E7's induction of DNA damage response, an activity mediated by E7's inactivation of pocket proteins.Human papillomavirus type 16 E7 perturbs DREAM to promote cellular proliferation and mitotic gene expression.Skin Tumors Rb(eing) Uncovered.Signaling pathways in HPV-associated cancers and therapeutic implications.Association of human papillomavirus with Fanconi anemia promotes carcinogenesis in Fanconi anemia patients.The human papillomavirus E7 oncoprotein as a regulator of transcription.A functional interaction of E7 with B-Myb-MuvB complex promotes acute cooperative transcriptional activation of both S- and M-phase genes. (129 c).Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation.
P2860
Q33774265-589EAB73-2D23-4514-9DA5-67F3776B6E48Q35005358-2D605730-2B05-4F73-987D-E7CED8C1F917Q36017174-E3B2F354-EE55-4A87-94F5-F297474791E7Q37198662-C454363F-8879-494E-9788-838314C6A816Q37270959-85C6108B-E845-4621-9723-177B2B948407Q37275914-1B4BCF04-6A3A-4620-98F2-B055BFEB30B6Q37537557-F7E10C23-BCB7-4D01-8548-61F8B1EE4274Q37558791-2950B8C1-97F9-47AC-A1D3-271095C0A2A5Q37722678-31B3D341-426F-4D77-9783-3C31D5788BECQ37728571-ECF7E437-1783-44F2-B457-18007C4D8414Q38175052-2049C9DA-A454-448C-883C-D3804F6B9434Q38370778-564344AB-C5AC-43BD-A1D2-F4483FFB2611Q38380216-8EC9317F-43A9-4302-990C-A7E4A817FE01Q39000409-CE03052F-915B-4AB6-8391-1B122E275630Q39076281-65845DC3-1AC6-4043-8831-5D43F99A15FEQ39102749-E0644F72-6F05-4065-968F-78BD1D96E46A
P2860
Inactivating all three rb family pocket proteins is insufficient to initiate cervical cancer.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Inactivating all three rb fami ...... t to initiate cervical cancer.
@ast
Inactivating all three rb fami ...... t to initiate cervical cancer.
@en
type
label
Inactivating all three rb fami ...... t to initiate cervical cancer.
@ast
Inactivating all three rb fami ...... t to initiate cervical cancer.
@en
prefLabel
Inactivating all three rb fami ...... t to initiate cervical cancer.
@ast
Inactivating all three rb fami ...... t to initiate cervical cancer.
@en
P2860
P1433
P1476
Inactivating all three rb fami ...... t to initiate cervical cancer.
@en
P2093
Myeong-Kyun Shin
Paul F Lambert
P2860
P304
P356
10.1158/0008-5472.CAN-12-2083
P407
P50
P577
2012-08-31T00:00:00Z