Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130
about
Gene expression analysis of forskolin treated basilar papillae identifies microRNA181a as a mediator of proliferation.The transcriptional coregulator RIP140 represses E2F1 activity and discriminates breast cancer subtypesRetinoblastoma family genesTransgenic Models in Retinoblastoma ResearchMurine models and cell lines for the investigation of pheochromocytoma: applications for future therapies?Repression by RB1 characterizes genes involved in the penultimate stage of erythroid developmentGFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumorsOsteosarcomagenesis: modeling cancer initiation in the mouse.Compensation by tumor suppressor genes during retinal development in mice and humans.Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursorsTandem E2F binding sites in the promoter of the p107 cell cycle regulator control p107 expression and its cellular functions.Dual loss of rb1 and Trp53 in the adrenal medulla leads to spontaneous pheochromocytoma.p107 in the public eye: an Rb understudy and more.Cancer models in Caenorhabditis elegans.The histone demethylase Jarid1b (Kdm5b) is a novel component of the Rb pathway and associates with E2f-target genes in MEFs during senescence.Development and potential applications of CRISPR-Cas9 genome editing technology in sarcoma.Tumor suppressor gene identification using retroviral insertional mutagenesis in Blm-deficient mice.DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly.Ablation of Kcnj10 expression in retinal explants revealed pivotal roles for Kcnj10 in the proliferation and development of Müller glia.p27Kip1 and p130 cooperate to regulate hematopoietic cell proliferation in vivo.Role of NEK2A in human cancer and its therapeutic potentials.Targeting Rb inactivation in cancers by synthetic lethality.mTORC1 maintains the tumorigenicity of SSEA-4(+) high-grade osteosarcoma.Structural mechanisms of DREAM complex assembly and regulation.Murine bilateral retinoblastoma exhibiting rapid-onset, metastatic progression and N-myc gene amplificationSelective requirements for E2f3 in the development and tumorigenicity of Rb-deficient chimeric tissues.Inactivating all three rb family pocket proteins is insufficient to initiate cervical cancer.A novel tumor suppressor network in squamous malignanciesRetinal horizontal cells lacking Rb1 sustain persistent DNA damage and survive as polyploid giant cells.Mouse models of sarcomas: critical tools in our understanding of the pathobiologyRegulation of the G1/S phase of the cell cycle and alterations in the RB pathway in human lung cancer.Technical challenges and limitations of current mouse models of ovarian cancer.Pocket protein function in melanocyte homeostasis and neoplasia.Retinoblastoma tumor suppressor protein-dependent methylation of histone H3 lysine 27 is associated with irreversible cell cycle exit.Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineagep21 suppresses inflammation and tumorigenesis on pRB-deficient stratified epithelia.Positive regulation of minichromosome maintenance gene expression, DNA replication, and cell transformation by a plant retinoblastoma gene.Established and new mouse models reveal E2f1 and Cdk2 dependency of retinoblastoma, and expose effective strategies to block tumor initiation.Insights from mouse models into human retinoblastomaThe retinoblastoma protein and its homolog p130 regulate the G1/S transition in pancreatic beta-cells.
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P2860
Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130
description
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Dezember 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/12/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/12/01)
@nl
наукова стаття, опублікована в грудні 2004
@uk
مقالة علمية (نشرت في ديسمبر 2004)
@ar
name
Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130
@ast
Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130
@en
Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130
@nl
type
label
Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130
@ast
Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130
@en
Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130
@nl
prefLabel
Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130
@ast
Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130
@en
Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130
@nl
P2093
P2860
P356
P1433
P1476
Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130
@en
P2093
Hein te Riele
Jan-Hermen Dannenberg
Leontine Schuijff
Marleen Dekker
Martin van der Valk
P2860
P304
P356
10.1101/GAD.322004
P577
2004-12-01T00:00:00Z