Glycosylation inhibition reduces cholesterol accumulation in NPC1 protein-deficient cells

Glycosylation inhibition reduces cholesterol accumulation in NPC1 protein-deficient cells

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http://www.wikidata.org/entity/Q36354918
How and why intralumenal membrane fragments form during vacuolar lysosome fusion.Structure of human Niemann-Pick C1 protein.Clues to the mechanism of cholesterol transfer from the structure of NPC1 middle lumenal domain bound to NPC2.Lysosomal membrane glycoproteins bind cholesterol and contribute to lysosomal cholesterol export.Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling.Activation of PKC triggers rescue of NPC1 patient specific iPSC derived glial cells from gliosis.Phosphatidylcholine: Greasing the Cholesterol Transport Machinery.The tonoplast--where sweetness is dispensable.A comprehensive overview of computational resources to aid in precision genome editing with engineered nucleases.Applications of CRISPR Genome Engineering in Cell Biology.PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder.Quantitative Analysis of the Proteome Response to the Histone Deacetylase Inhibitor (HDACi) Vorinostat in Niemann-Pick Type C1 disease.Utility of rapid whole-exome sequencing in the diagnosis of Niemann-Pick disease type C presenting with fetal hydrops and acute liver failure.Image-based drug screen identifies HDAC inhibitors as novel Golgi disruptors synergizing with JQ1.Quantitative Measurement of Cholesterol in Cell Populations Using Flow Cytometry and Fluorescent Perfringolysin O.The Nutrient-Sensing Hexosamine Biosynthetic Pathway as the Hub of Cancer Metabolic Rewiring.
P2860

Glycosylation inhibition reduces cholesterol accumulation in NPC1 protein-deficient cells

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http://www.wikidata.org/entity/Q36354918
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Glycosylation inhibition reduces cholesterol accumulation in NPC1 protein-deficient cells
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Glycosylation inhibition reduces cholesterol accumulation in NPC1 protein-deficient cells
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Glycosylation inhibition reduces cholesterol accumulation in NPC1 protein-deficient cells
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Glycosylation inhibition reduces cholesterol accumulation in NPC1 protein-deficient cells
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Glycosylation inhibition reduces cholesterol accumulation in NPC1 protein-deficient cells
@ast
Glycosylation inhibition reduces cholesterol accumulation in NPC1 protein-deficient cells
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Glycosylation inhibition reduces cholesterol accumulation in NPC1 protein-deficient cells
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932