Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone. - Test2 - elhamkhani - TriplyDB

Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone.

Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone.

http://www.wikidata.org/entity/Q36377205

about

Molecular mimicry, bystander activation, or viral persistence: infections and autoimmune disease.A virus-induced molecular mimicry model of multiple sclerosis Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection Crossreactivity of a human autoimmune TCR is dominated by a single TCR loop Deconstructing the Peptide-MHC Specificity of T Cell Recognition Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein Multiple Sclerosis and T Lymphocytes: An Entangled Story T-cell vaccination for autoimmune diseases: immunologic lessons and clinical experience in multiple sclerosis Minimal peptide length requirements for CD4(+) T cell clones--implications for molecular mimicry and T cell survival.Advances in the use of synthetic combinatorial chemistry: mixture-based libraries.Peptide vaccines and peptide libraries.Clonal expansion of freshly isolated CD4T cells by randomized peptides and identification of peptide ligands using combinatorial peptide libraries.Synaptojanin 2 is recognized by HLA class II-restricted hairy cell leukemia-specific T cells.Glatiramer acetate (Copaxone) induces degenerate, Th2-polarized immune responses in patients with multiple sclerosis.Cerebrospinal fluid-infiltrating CD4+ T cells recognize Borrelia burgdorferi lysine-enriched protein domains and central nervous system autoantigens in early lyme encephalitis Molecular mimicry and multiple sclerosis: degenerate T-cell recognition and the induction of autoimmunity.Molecular mimics can induce a nonautoaggressive repertoire that preempts induction of autoimmunity.Role of autoreactive CD8+ T cells in organ-specific autoimmune diseases: insight from transgenic mouse models.Sequence and Structural Analyses Reveal Distinct and Highly Diverse Human CD8+ TCR Repertoires to Immunodominant Viral Antigens Manipulating antigenic ligand strength to selectively target myelin-reactive CD4+ T cells in EAE.Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule Central nervous system pathology caused by autoreactive CD8+ T-cell clones following virus infection Infection, mimics, and autoimmune disease.Apoptosis of inflammatory cells in immune control of the nervous system: role of glia.Mechanisms for the induction of autoimmunity by infectious agents.Diversity-oriented approaches for interrogating T-cell receptor repertoire, ligand recognition, and function Degeneracy, as opposed to specificity, in immunotherapy.A two-step, two-signal model for the primary activation of precursor helper T cells Specificity, degeneracy, and molecular mimicry in antigen recognition by HLA-Class II restricted T cell receptors: implications for clinical medicine.Human CD4+ T cell responses to the dog major allergen Can f 1 and its human homologue tear lipocalin resemble each other T-cell-mediated autoimmunity: novel techniques to characterize autoreactive T-cell receptors A single autoimmune T cell receptor recognizes more than a million different peptides.Heteroclitic proliferative responses and changes in cytokine profile induced by altered peptides: implications for autoimmunity.Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors.Cumulative autoimmunity: T cell clones recognizing several self-epitopes exhibit enhanced pathogenicity Unusual features of self-peptide/MHC binding by autoimmune T cell receptors Kinetics and thermodynamics of T cell receptor- autoantigen interactions in murine experimental autoimmune encephalomyelitis.Expression and crystallization of the complex of HLA-DR2 (DRA, DRB1*1501) and an immunodominant peptide of human myelin basic protein CD8(+) T cells mediate CD40-independent maturation of dendritic cells in vivo Microbial epitopes act as altered peptide ligands to prevent experimental autoimmune encephalomyelitis

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P2860

Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone.

http://www.wikidata.org/entity/Q36377205

description

1997 nî lūn-bûn

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1997年の論文

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1997年学术文章

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1997年学术文章

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1997年学术文章

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1997年学术文章

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1997年学术文章

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1997年學術文章

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1997年學術文章

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1997年學術文章

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name

Identification of high potency ...... ss II-restricted T cell clone.

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Identification of high potency ...... ss II-restricted T cell clone.

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type

label

Identification of high potency ...... ss II-restricted T cell clone.

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Identification of high potency ...... ss II-restricted T cell clone.

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Identification of high potency ...... ss II-restricted T cell clone.

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Identification of high potency ...... ss II-restricted T cell clone.

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Journal of Experimental Medicine

P1476

Identification of high potency ...... ss II-restricted T cell clone.

@en

P2093

B Hemmer

http://www.w3.org/2001/XMLSchema#string

B T Fleckenstein

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G Jung

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H McFarland

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K H Wiesmüller

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M Vergelli

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R Martin

http://www.w3.org/2001/XMLSchema#string

P2860

The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

SH2 domains recognize specific phosphopeptide sequences

Rapid identification of high affinity peptide ligands using positional scanning synthetic peptide combinatorial libraries.

Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery.

Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein.

A myelin basic protein peptide is recognized by cytotoxic T cells in the context of four HLA-DR types associated with multiple sclerosis

Use of combinatorial peptide libraries to construct functional mimics of tumor epitopes recognized by MHC class I-restricted cytolytic T lymphocytes

The use of dedicated peptide libraries permits the discovery of high affinity binding peptides.

Decrypting the structure of major histocompatibility complex class I-restricted cytotoxic T lymphocyte epitopes with complex peptide libraries.

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9

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185

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1997-05-01T00:00:00Z

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236258292

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9151902

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2196302

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