Decreased nociceptive sensitization in mice lacking the fragile X mental retardation protein: role of mGluR1/5 and mTOR
about
Fragile X syndrome: loss of local mRNA regulation alters synaptic development and functionFMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autismModifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses.Genetic disruption of voltage-gated calcium channels in psychiatric and neurological disordersAMPK: An emerging target for modification of injury-induced pain plasticity.CPEB3 Deficiency Elevates TRPV1 Expression in Dorsal Root Ganglia Neurons to Potentiate ThermosensationA Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons.mTOR, a new potential target for chronic pain and opioid-induced tolerance and hyperalgesiaCommonalities between pain and memory mechanisms and their meaning for understanding chronic painFragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel densityTranslational control of nociception via 4E-binding protein 1Activation of mammalian target of rapamycin contributes to pain nociception induced in rats by BmK I, a sodium channel-specific modulatorAdenosine Monophosphate-activated Protein Kinase (AMPK) Activators For the Prevention, Treatment and Potential Reversal of Pathological Pain.Resilience to audiogenic seizures is associated with p-ERK1/2 dephosphorylation in the subiculum of Fmr1 knockout mice.Genetic reduction of muscarinic M4 receptor modulates analgesic response and acoustic startle response in a mouse model of fragile X syndrome (FXS).The role of fragile X mental retardation protein in major mental disorders.Local translation in primary afferent fibers regulates nociceptionRepetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP.Fragile X targeted pharmacotherapy: lessons learned and future directions.Expression and distribution of mTOR, p70S6K, 4E-BP1, and their phosphorylated counterparts in rat dorsal root ganglion and spinal cord dorsal hornmTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK.Mammalian target of rapamycin signaling in the spinal cord is required for neuronal plasticity and behavioral hypersensitivity associated with neuropathy in the rat.Fragile X mental retardation protein regulates protein expression and mRNA translation of the potassium channel Kv4.2.Spinal phosphinositide 3-kinase-Akt-mammalian target of rapamycin signaling cascades in inflammation-induced hyperalgesiamTOR kinase: a possible pharmacological target in the management of chronic pain.Genetic reduction of group 1 metabotropic glutamate receptors alters select behaviors in a mouse model for fragile X syndrome.Dendritic spine dysgenesis contributes to hyperreflexia after spinal cord injury.Gene expression profiling in pachyonychia congenita skinFragile X mental retardation protein (FMRP) and the spinal sensory system.Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond.Self-injurious behaviour in intellectual disability syndromes: evidence for aberrant pain signalling as a contributing factor.Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain.Spinal cord NMDA receptor-mediated activation of mammalian target of rapamycin is required for the development and maintenance of bone cancer-induced pain hypersensitivities in rats.The pharmacology of nociceptor primingDysregulation of fragile × mental retardation protein and metabotropic glutamate receptor 5 in superior frontal cortex of individuals with autism: a postmortem brain study.mTOR and its downstream pathway are activated in the dorsal root ganglion and spinal cord after peripheral inflammation, but not after nerve injuryDysregulation of mTOR signaling in fragile X syndrome.Protein kinase B/Akt is required for complete Freund's adjuvant-induced upregulation of Nav1.7 and Nav1.8 in primary sensory neurons.Peripheral administration of translation inhibitors reverses increased hyperalgesia in a model of chronic pain in the rat.Behavioral Phenotype of Fmr1 Knock-Out Mice during Active Phase in an Altered Light/Dark Cycle.
P2860
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P2860
Decreased nociceptive sensitization in mice lacking the fragile X mental retardation protein: role of mGluR1/5 and mTOR
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
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2007年學術文章
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name
Decreased nociceptive sensitiz ...... ein: role of mGluR1/5 and mTOR
@ast
Decreased nociceptive sensitiz ...... ein: role of mGluR1/5 and mTOR
@en
type
label
Decreased nociceptive sensitiz ...... ein: role of mGluR1/5 and mTOR
@ast
Decreased nociceptive sensitiz ...... ein: role of mGluR1/5 and mTOR
@en
prefLabel
Decreased nociceptive sensitiz ...... ein: role of mGluR1/5 and mTOR
@ast
Decreased nociceptive sensitiz ...... ein: role of mGluR1/5 and mTOR
@en
P2093
P2860
P1476
Decreased nociceptive sensitiz ...... ein: role of mGluR1/5 and mTOR
@en
P2093
Fernando Cervero
Jose M Entrena
Magali Millecamps
Md Harunor Rashid
Raul Sanoja
P2860
P304
13958-13967
P356
10.1523/JNEUROSCI.4383-07.2007
P407
P577
2007-12-01T00:00:00Z