Deletion of FMR1 in Purkinje cells enhances parallel fiber LTD, enlarges spines, and attenuates cerebellar eyelid conditioning in Fragile X syndrome
about
X-linked disorders with cerebellar dysgenesisCorrection of fragile X syndrome in mice.Emerging pharmacotherapies for neurodevelopmental disordersGroup 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and diseaseAdvances in the treatment of fragile X syndromeA pilot open label, single dose trial of fenobam in adults with fragile X syndrome.Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X SyndromeMouse Genetic Models of Human Brain DisordersThe 40-year history of modeling active dendrites in cerebellar Purkinje cells: emergence of the first single cell "community model"The role of cerebellar circuitry alterations in the pathophysiology of autism spectrum disordersThe impact of hippocampal lesions on trace-eyeblink conditioning and forebrain-cerebellar interactionsSynaptic plasticity, neural circuits, and the emerging role of altered short-term information processing in schizophrenia.Fragile X syndrome and targeted treatment trials.Dendritic spine dysgenesis in autism related disordersThe contribution of inhibitory interneurons to circuit dysfunction in Fragile X SyndromeThe pathophysiology of fragile X (and what it teaches us about synapses)Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice.The Intense World Theory – A Unifying Theory of the Neurobiology of AutismLTD-like molecular pathways in developmental synaptic pruningA Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons.Synaptic plasticity: multiple forms, functions, and mechanismsProteomic studies of a single CNS synapse type: the parallel fiber/purkinje cell synapseEnhancement of both long-term depression induction and optokinetic response adaptation in mice lacking delphilinFragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptorsTrace Eyeblink Conditioning in Mice Is Dependent upon the Dorsal Medial Prefrontal Cortex, Cerebellum, and Amygdala: Behavioral Characterization and Functional Circuitry(1,2,3).The cerebellum, sensitive periods, and autism.HCN1 channels in cerebellar Purkinje cells promote late stages of learning and constrain synaptic inhibitionChildren with autism spectrum disorders show abnormal conditioned response timing on delay, but not trace, eyeblink conditioning.Fragile X: leading the way for targeted treatments in autism.Pre-clinical models of neurodevelopmental disorders: focus on the cerebellumReevaluation of the role of parallel fiber synapses in delay eyeblink conditioning in mice using Cbln1 as a tool.Deep cerebellar nuclei play an important role in two-tone discrimination on delay eyeblink conditioning in C57BL/6 mice.Temporal patterns of inputs to cerebellum necessary and sufficient for trace eyelid conditioning.Cerebellar and extracerebellar involvement in mouse eyeblink conditioning: the ACDC model.Lock-and-key mechanisms of cerebellar memory recall based on rebound currents.A mouse model of the human Fragile X syndrome I304N mutation.Elevated glycogen synthase kinase-3 activity in Fragile X mice: key metabolic regulator with evidence for treatment potential.Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice.Pharmacological rescue of cortical synaptic and network potentiation in a mouse model for fragile X syndromeCerebellar plasticity and motor learning deficits in a copy-number variation mouse model of autism.
P2860
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P2860
Deletion of FMR1 in Purkinje cells enhances parallel fiber LTD, enlarges spines, and attenuates cerebellar eyelid conditioning in Fragile X syndrome
description
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im August 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/08/04)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/08/04)
@nl
наукова стаття, опублікована в серпні 2005
@uk
مقالة علمية (نشرت في 4-8-2005)
@ar
name
Deletion of FMR1 in Purkinje c ...... itioning in Fragile X syndrome
@ast
Deletion of FMR1 in Purkinje c ...... itioning in Fragile X syndrome
@en
Deletion of FMR1 in Purkinje c ...... itioning in Fragile X syndrome
@nl
type
label
Deletion of FMR1 in Purkinje c ...... itioning in Fragile X syndrome
@ast
Deletion of FMR1 in Purkinje c ...... itioning in Fragile X syndrome
@en
Deletion of FMR1 in Purkinje c ...... itioning in Fragile X syndrome
@nl
prefLabel
Deletion of FMR1 in Purkinje c ...... itioning in Fragile X syndrome
@ast
Deletion of FMR1 in Purkinje c ...... itioning in Fragile X syndrome
@en
Deletion of FMR1 in Purkinje c ...... itioning in Fragile X syndrome
@nl
P2093
P921
P3181
P1433
P1476
Deletion of FMR1 in Purkinje c ...... itioning in Fragile X syndrome
@en
P2093
De Graaf W
De Zeeuw CI
Dortland BR
Kakizawa S
Koekkoek SK
Mientjes E
P304
P3181
P356
10.1016/J.NEURON.2005.07.005
P407
P577
2005-08-01T00:00:00Z