Intrinsic voltage dependence and Ca2+ regulation of mslo large conductance Ca-activated K+ channels.
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Molecular basis of fast inactivation in voltage and Ca2+-activated K+ channels: a transmembrane beta-subunit homologCloning and functional characterization of novel large conductance calcium-activated potassium channel beta subunits, hKCNMB3 and hKCNMB4Functional coupling of intracellular calcium and inactivation of voltage-gated Kv1.1/Kvbeta1.1 A-type K+ channelsGain-of-function mutation in the KCNMB1 potassium channel subunit is associated with low prevalence of diastolic hypertensionLarge conductance voltage- and calcium-dependent K+ channel, a distinct member of voltage-dependent ion channels with seven N-terminal transmembrane segments (S0-S6), an extracellular N terminus, and an intracellular (S9-S10) C terminusInactivation of BK channels mediated by the NH(2) terminus of the beta3b auxiliary subunit involves a two-step mechanism: possible separation of binding and blockadeGating properties conferred on BK channels by the beta3b auxiliary subunit in the absence of its NH(2)- and COOH terminiSlo3 K+ channels: voltage and pH dependence of macroscopic currentsExamining synaptotagmin 1 function in dense core vesicle exocytosis under direct control of Ca2+BK channels: multiple sensors, one activation gateNMR structure of the "ball-and-chain" domain of KCNMB2, the beta 2-subunit of large conductance Ca2+- and voltage-activated potassium channelsRole of the S4 segment in a voltage-dependent calcium-sensitive potassium (hSlo) channelDihydroxyeicosatrienoic acids are potent activators of Ca(2+)-activated K(+) channels in isolated rat coronary arterial myocytesFunctional effects of auxiliary beta4-subunit on rat large-conductance Ca(2+)-activated K(+) channelStimulatory action of internal protons on Slo1 BK channelsRenin-angiotensin system expression and secretory function in cultured human ciliary body non-pigmented epithelium.Voltage dependence of the coupling of Ca(2+) sparks to BK(Ca) channels in urinary bladder smooth muscle.Alpha5beta1 integrin engagement increases large conductance, Ca2+-activated K+ channel current and Ca2+ sensitivity through c-src-mediated channel phosphorylation.A BK (Slo1) channel journey from molecule to physiology.Theophylline inhibits the cough reflex through a novel mechanism of action.Coupling and cooperativity in voltage activation of a limited-state BK channel gating in saturating Ca2+.An alcohol-sensing site in the calcium- and voltage-gated, large conductance potassium (BK) channel.An epilepsy/dyskinesia-associated mutation enhances BK channel activation by potentiating Ca2+ sensing.Stepwise contribution of each subunit to the cooperative activation of BK channels by Ca2+.Two distinct pools of large-conductance calcium-activated potassium channels in the somatic plasma membrane of central principal neuronsIs there a role for potassium channel openers in neuronal ion channel disorders?A charged residue in S4 regulates coupling among the activation gate, voltage, and Ca2+ sensors in BK channels.Complex voltage-dependent behavior of single unliganded calcium-sensitive potassium channels.Modeling hair cell tuning by expression gradients of potassium channel beta subunits.Variants of the KCNMB3 regulatory subunit of maxi BK channels affect channel inactivation.Ion sensing in the RCK1 domain of BK channels.Large conductance, Ca2+-activated K+ channels (BKCa) and arteriolar myogenic signalingVoltage- and cold-dependent gating of single TRPM8 ion channels.Setting the stage for molecular dissection of the regulatory components of BK channels.Single-channel kinetics of BK (Slo1) channels.Voltage-dependent conformational changes in human Ca(2+)- and voltage-activated K(+) channel, revealed by voltage-clamp fluorometry.Tuning magnesium sensitivity of BK channels by mutations.Molecular mechanisms underlying the effect of the novel BK channel opener GoSlo: involvement of the S4/S5 linker and the S6 segment.Charge substitution for a deep-pore residue reveals structural dynamics during BK channel gating.Ca2+-binding activity of a COOH-terminal fragment of the Drosophila BK channel involved in Ca2+-dependent activation.
P2860
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P2860
Intrinsic voltage dependence and Ca2+ regulation of mslo large conductance Ca-activated K+ channels.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Intrinsic voltage dependence a ...... ance Ca-activated K+ channels.
@ast
Intrinsic voltage dependence a ...... ance Ca-activated K+ channels.
@en
type
label
Intrinsic voltage dependence a ...... ance Ca-activated K+ channels.
@ast
Intrinsic voltage dependence a ...... ance Ca-activated K+ channels.
@en
prefLabel
Intrinsic voltage dependence a ...... ance Ca-activated K+ channels.
@ast
Intrinsic voltage dependence a ...... ance Ca-activated K+ channels.
@en
P2093
P2860
P356
P1476
Intrinsic voltage dependence a ...... ance Ca-activated K+ channels.
@en
P2093
P2860
P304
P356
10.1085/JGP.109.5.647
P577
1997-05-01T00:00:00Z