Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes

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PIK3CA mutations and TP53 alterations cooperate to increase cancerous phenotypes and tumor heterogeneity.Increased centrosome number in BRCA-related breast cancer specimens determined by immunofluorescence analysis.

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Q38716747-E5BC18C0-12CF-4674-82AB-006AC0A9570E Q51758191-2099017B-7CD1-4503-B757-3B723652C4CF

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Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes

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Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes

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Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes

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Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes

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Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes

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Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes

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Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes

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P1476

Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes

@en

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Alan K Meeker

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Ben Ho Park

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Bracha Erlanger

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Christopher M Heaphy

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Daniel J Zabransky

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David Chu

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Heather Parsons

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Hong Yuen Wong

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Julia A Beaver

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Justin Cidado

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Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155

53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

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25240-25251

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scholarly article

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10.18632/ONCOTARGET.4595

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English

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Josh Lauring

Sarah Croessmann

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2015-09-01T00:00:00Z

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280911252

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26246475

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P932

4694828

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Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes

about

P2860

P2860

Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P5875

P698

P932