Spliceosome activation: U4 is the path, stem I is the goal, and Prp8 is the keeper. Let's cheer for the ATPase Brr2!
about
RNA helicase proteins as chaperones and remodelersPrp8 retinitis pigmentosa mutants cause defects in the transition between the catalytic steps of splicing.A mutation in a splicing factor that causes retinitis pigmentosa has a transcriptome-wide effect on mRNA splicing.A multi-step model for facilitated unwinding of the yeast U4/U6 RNA duplex.Protein localisation by electron microscopy reveals the architecture of the yeast spliceosomal B complex.
P2860
Spliceosome activation: U4 is the path, stem I is the goal, and Prp8 is the keeper. Let's cheer for the ATPase Brr2!
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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name
Spliceosome activation: U4 is ...... t's cheer for the ATPase Brr2!
@ast
Spliceosome activation: U4 is ...... t's cheer for the ATPase Brr2!
@en
type
label
Spliceosome activation: U4 is ...... t's cheer for the ATPase Brr2!
@ast
Spliceosome activation: U4 is ...... t's cheer for the ATPase Brr2!
@en
prefLabel
Spliceosome activation: U4 is ...... t's cheer for the ATPase Brr2!
@ast
Spliceosome activation: U4 is ...... t's cheer for the ATPase Brr2!
@en
P2860
P356
P1433
P1476
Spliceosome activation: U4 is ...... t's cheer for the ATPase Brr2!
@en
P2093
Jonathan P Staley
Klaus H Nielsen
P2860
P304
P356
10.1101/GAD.207514.112
P577
2012-11-01T00:00:00Z