A quantitative assay for assessing the effects of DNA lesions on transcription - Test2 - elhamkhani - TriplyDB

A quantitative assay for assessing the effects of DNA lesions on transcription

A quantitative assay for assessing the effects of DNA lesions on transcription

http://www.wikidata.org/entity/Q36431367

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Transcriptional mutagenesis and its potential roles in the etiology of cancer and bacterial antibiotic resistance Mass spectrometry for the assessment of the occurrence and biological consequences of DNA adducts Structural basis for the recognition of diastereomeric 5',8-cyclo-2'-deoxypurine lesions by the human nucleotide excision repair system Reactivity of Nucleic Acid Radicals.Generation of guanine-amino acid cross-links by a free radical combination mechanism A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses.Effects of Tet-mediated oxidation products of 5-methylcytosine on DNA transcription in vitro and in mammalian cells.Transcriptional bypass of regioisomeric ethylated thymidine lesions by T7 RNA polymerase and human RNA polymerase II.Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions.Transcriptional inhibition and mutagenesis induced by N-nitroso compound-derived carboxymethylated thymidine adducts in DNA.Radiation-induced formation of purine lesions in single and double stranded DNA: revised quantification.Oxidatively Generated Guanine(C8)-Thymine(N3) Intrastrand Cross-links in Double-stranded DNA Are Repaired by Base Excision Repair Pathways.An ameliorative protocol for the quantification of purine 5',8-cyclo-2'-deoxynucleosides in oxidized DNA.Identification of DNA lesions using a third base pair for amplification and nanopore sequencing.Effects of 6-thioguanine and S6-methylthioguanine on transcription in vitro and in human cells.Quantitative measurement of transcriptional inhibition and mutagenesis induced by site-specifically incorporated DNA lesions in vitro and in vivo Sequencing of DNA Lesions Facilitated by Site-Specific Excision via Base Excision Repair DNA Glycosylases Yielding Ligatable Gaps.Bidirectional transcription of trinucleotide repeats: roles for excision repair.Identification of novel α-n-methylation of CENP-B that regulates its binding to the centromeric DNA.Translesion synthesis of 8,5'-cyclopurine-2'-deoxynucleosides by DNA polymerases η, ι, and ζ.Roles of Aag, Alkbh2, and Alkbh3 in the Repair of Carboxymethylated and Ethylated Thymidine Lesions Induction of 8,5'-cyclo-2'-deoxyadenosine and 8,5'-cyclo-2'-deoxyguanosine in isolated DNA by Fenton-type reagents Mass Spectrometry-Based Quantitative Strategies for Assessing the Biological Consequences and Repair of DNA Adducts.6-thioguanine induces mitochondrial dysfunction and oxidative DNA damage in acute lymphoblastic leukemia cells.Oxidative DNA damage is epigenetic by regulating gene transcription via base excision repair.Epimeric 2-deoxyribose lesions: Products from the improper chemical repair of 2-deoxyribose radicals.Quantitative and in situ detection of oxidatively generated DNA damage 8,5'-cyclo-2'-deoxyadenosine using an immunoassay with a novel monoclonal antibody.Occurrence, Biological Consequences, and Human Health Relevance of Oxidative Stress-Induced DNA Damage.RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications.The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RNA Polymerase II Elongation in Vitro.Purine 5',8-cyclo-2'-deoxynucleoside lesions: formation by radical stress and repair in human breast epithelial cancer cells.Chemical Analysis of DNA Damage.Mechanism of DNA alkylation-induced transcriptional stalling, lesion bypass, and mutagenesis.Mechanism of RNA polymerase II stalling by DNA alkylation.A lipophilic "fully-anti" dodecamer from a (5'S)-5',8-cyclo-2'-deoxyguanosine

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A quantitative assay for assessing the effects of DNA lesions on transcription

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description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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name

A quantitative assay for assessing the effects of DNA lesions on transcription

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A quantitative assay for assessing the effects of DNA lesions on transcription

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A quantitative assay for assessing the effects of DNA lesions on transcription

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A quantitative assay for assessing the effects of DNA lesions on transcription

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A quantitative assay for assessing the effects of DNA lesions on transcription

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Nature Chemical Biology

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A quantitative assay for assessing the effects of DNA lesions on transcription

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Changjun You

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Jianshuang Wang

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Jin Wang

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Laura J Niedernhofer

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Philip J Brooks

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Xiaoxia Dai

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Yinsheng Wang

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P2860

Instability and decay of the primary structure of DNA

Mutagenesis, genotoxicity, and repair of 1-methyladenine, 3-alkylcytosines, 1-methylguanine, and 3-methylthymine in alkB Escherichia coli

Transcriptional mutagenesis induced by 8-oxoguanine in mammalian cells

Transcription-coupled DNA repair: two decades of progress and surprises

High-throughput analysis of the mutagenic and cytotoxic properties of DNA lesions by next-generation sequencing.

Removal of oxygen free-radical-induced 5',8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cells

The 8,5'-cyclopurine-2'-deoxynucleosides: candidate neurodegenerative DNA lesions in xeroderma pigmentosum, and unique probes of transcription and nucleotide excision repair.

Abasic sites and strand breaks in DNA cause transcriptional mutagenesis in Escherichia coli.

Dynamic flexibility of DNA repair pathways in growth arrested Escherichia coli

Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli

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10.1038/NCHEMBIO.1046

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8

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1020426024

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