Class I ribonucleotide reductases: metallocofactor assembly and repair in vitro and in vivo.
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Mechanisms for control of biological electron transfer reactionsIron-containing urease in a pathogenic bacteriumA Radical Transfer Pathway in Spore Photoproduct LyaseThe Dimanganese(II) Site of Bacillus subtilis Class Ib Ribonucleotide ReductaseRole of Arginine 293 and Glutamine 288 in Communication between Catalytic and Allosteric Sites in Yeast Ribonucleotide ReductaseStructural Basis for Assembly of the Mn IV /Fe III Cofactor in the Class Ic Ribonucleotide Reductase from Chlamydia trachomatisStreptococcus sanguinis Class Ib Ribonucleotide ReductaseA dynamic C-terminal segment in the Mycobacterium tuberculosis Mn/Fe R2lox protein can adopt a helical structure with possible functional consequencesYeast Dun1 Kinase Regulates Ribonucleotide Reductase Small Subunit Localization in Response to Iron Deficiency.The iron metallome in eukaryotic organismsIdentification of a cyclic nucleotide as a cryptic intermediate in molybdenum cofactor biosynthesisMethyl-hydroxylamine as an efficacious antibacterial agent that targets the ribonucleotide reductase enzymeBiochemical Characterization of the Split Class II Ribonucleotide Reductase from Pseudomonas aeruginosaThe origin and evolution of ribonucleotide reductionA novel clade of unique eukaryotic ribonucleotide reductase R2 subunits is exclusive to apicomplexan parasitesX-ray Scattering Studies of Protein Structural Dynamics.The conserved Lys-95 charged residue cluster is critical for the homodimerization and enzyme activity of human ribonucleotide reductase small subunit M2At the Interface of Chemical and Biological Synthesis: An Expanded Genetic Code.Structural Basis for Oxygen Activation at a Heterodinuclear Manganese/Iron Cofactor.Iron mediates catalysis of nucleic acid processing enzymes: support for Fe(II) as a cofactor before the great oxidation event.Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA ReplicationConserved electron donor complex Dre2-Tah18 is required for ribonucleotide reductase metallocofactor assembly and DNA synthesisRibonucleotide reductase metallocofactor: assembly, maintenance and inhibition.The structural basis for the allosteric regulation of ribonucleotide reductase.Yeast Dun1 kinase regulates ribonucleotide reductase inhibitor Sml1 in response to iron deficiencyDistinct mechanisms of cell-kill by triapine and its terminally dimethylated derivative Dp44mT due to a loss or gain of activity of their copper(II) complexes.Choosing the right metal: case studies of class I ribonucleotide reductasesRapid X-ray photoreduction of dimetal-oxygen cofactors in ribonucleotide reductase.Bacillus subtilis class Ib ribonucleotide reductase is a dimanganese(III)-tyrosyl radical enzyme.Regulation of ribonucleotide reductase in response to iron deficiency.Investigation of in vivo diferric tyrosyl radical formation in Saccharomyces cerevisiae Rnr2 protein: requirement of Rnr4 and contribution of Grx3/4 AND Dre2 proteinsSignificant Improvement of Oxidase Activity through the Genetic Incorporation of a Redox-active Unnatural Amino Acid.Substrate specificity characterization for eight putative nudix hydrolases. Evaluation of criteria for substrate identification within the Nudix family.Mechanistic studies of the spore photoproduct lyase via a single cysteine mutationMechanistic studies of semicarbazone triapine targeting human ribonucleotide reductase in vitro and in mammalian cells: tyrosyl radical quenching not involving reactive oxygen species.Targeting the Large Subunit of Human Ribonucleotide Reductase for Cancer Chemotherapy.Metallation and mismetallation of iron and manganese proteins in vitro and in vivo: the class I ribonucleotide reductases as a case studyInvestigation of in vivo roles of the C-terminal tails of the small subunit (ββ') of Saccharomyces cerevisiae ribonucleotide reductase: contribution to cofactor formation and intersubunit association within the active holoenzyme.Crystal Structure and Catalytic Mechanism of 7-Hydroxymethyl Chlorophyll a Reductase.Mechanism of assembly of the dimanganese-tyrosyl radical cofactor of class Ib ribonucleotide reductase: enzymatic generation of superoxide is required for tyrosine oxidation via a Mn(III)Mn(IV) intermediate
P2860
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P2860
Class I ribonucleotide reductases: metallocofactor assembly and repair in vitro and in vivo.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Class I ribonucleotide reducta ...... d repair in vitro and in vivo.
@ast
Class I ribonucleotide reducta ...... d repair in vitro and in vivo.
@en
type
label
Class I ribonucleotide reducta ...... d repair in vitro and in vivo.
@ast
Class I ribonucleotide reducta ...... d repair in vitro and in vivo.
@en
prefLabel
Class I ribonucleotide reducta ...... d repair in vitro and in vivo.
@ast
Class I ribonucleotide reducta ...... d repair in vitro and in vivo.
@en
P2860
P1476
Class I ribonucleotide reducta ...... nd repair in vitro and in vivo
@en
P2093
Joanne Stubbe
P2860
P304
P356
10.1146/ANNUREV-BIOCHEM-061408-095817
P577
2011-01-01T00:00:00Z