The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses
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Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogrammingSIRTain regulators of premature senescence and accelerated agingSirtuins in Cancer: a Balancing Act between Genome Stability and MetabolismThe Key Role of Calmodulin in KRAS-Driven AdenocarcinomasSirtuins in metabolism, DNA repair and cancerSirtuin deacylases: a molecular link between metabolism and immunityGemcitabine induces poly (ADP-ribose) polymerase-1 (PARP-1) degradation through autophagy in pancreatic cancerLigand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349.Emerging role of sirtuins on tumorigenesis: possible link between aging and cancerSIRT3 & SIRT7: Potential Novel Biomarkers for Determining Outcome in Pancreatic Cancer Patients.SIRT6 Depletion Suppresses Tumor Growth by Promoting Cellular Senescence Induced by DNA Damage in HCC.1H NMR Metabolomics Reveals Association of High Expression of Inositol 1, 4, 5 Trisphosphate Receptor and Metabolites in Breast Cancer PatientsWhen Anti-Aging Studies Meet Cancer Chemoprevention: Can Anti-Aging Agent Kill Two Birds with One Blow?Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cellsHistone deacetylases and mechanisms of regulation of gene expressionAntitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model.A miR-34a-SIRT6 axis in the squamous cell differentiation networkHepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6The emerging and diverse roles of sirtuins in cancer: a clinical perspective.Upregulation of SIRT6 predicts poor prognosis and promotes metastasis of non-small cell lung cancer via the ERK1/2/MMP9 pathway.Sirtuins and cancer: new insights and cell signaling.TRP channels and STIM/ORAI proteins: sensors and effectors of cancer and stroma cell migrationSirt6 regulates dendritic cell differentiation, maturation, and function.Principles of K-Ras effector organization and the role of oncogenic K-Ras in cancer initiation through G1 cell cycle deregulation.Astragaloside IV sensitizes non-small cell lung cancer cells to gefitinib potentially via regulation of SIRT6.Sirtuin SIRT6 suppresses cell proliferation through inhibition of Twist1 expression in non-small cell lung cancer.SIRT6: Novel Mechanisms and Links to Aging and Disease.Inhibition of SIRT6 in prostate cancer reduces cell viability and increases sensitivity to chemotherapeutics.Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin.Sirtuin 6 contributes to migration and invasion of osteosarcoma cells via the ERK1/2/MMP9 pathway.The guardian: metabolic and tumour-suppressive effects of SIRT6.SIRT6 regulates the cigarette smoke-induced signalling in rheumatoid arthritis synovial fibroblasts.MicroRNA-186 suppresses lung cancer progression by targeting SIRT6.Aberrant SIRT6 expression contributes to melanoma growth: Role of the autophagy paradox and IGF-AKT signaling.Hexokinase 2 and nuclear factor erythroid 2-related factor 2 transcriptionally coactivate xanthine oxidoreductase expression in stressed glioma cells.Gene expressions of TRP channels in glioblastoma multiforme and relation with survival.Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic.Downregulation of SIRT6 by miR-34c-5p is associated with poor prognosis and promotes colon cancer proliferation through inhibiting apoptosis via the JAK2/STAT3 signaling pathway.Low Rap1-interacting factor 1 and sirtuin 6 expression predict poor outcome in radiotherapy-treated Hodgkin lymphoma patients.TRPM2 promotes the proliferation and invasion of pancreatic ductal adenocarcinoma.
P2860
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P2860
The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
The NAD+-dependent histone dea ...... s by regulating Ca2+ responses
@ast
The NAD+-dependent histone dea ...... s by regulating Ca2+ responses
@en
type
label
The NAD+-dependent histone dea ...... s by regulating Ca2+ responses
@ast
The NAD+-dependent histone dea ...... s by regulating Ca2+ responses
@en
prefLabel
The NAD+-dependent histone dea ...... s by regulating Ca2+ responses
@ast
The NAD+-dependent histone dea ...... s by regulating Ca2+ responses
@en
P2093
P2860
P356
P1476
The NAD+-dependent histone dea ...... s by regulating Ca2+ responses
@en
P2093
Alberto Ballestrero
Alessandro Poggi
Alessia Grozio
Alessio Nencioni
Debora Soncini
Denise Lasigliè
Franco Patrone
Gabriele Zoppoli
Georg Feldmann
Giovanna Basile
P2860
P304
40924-40937
P356
10.1074/JBC.M112.405837
P407
P577
2012-10-18T00:00:00Z