Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer

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Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer.

P2860

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Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer

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2015 nî lūn-bûn

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Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer

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Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer

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Item

label

Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer

@ast

Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer

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Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer

@ast

Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer

@en

P1476

Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer

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Alka Choudhary

http://www.w3.org/2001/XMLSchema#string

Amber Lasek

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Beth A Weaver

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Brittany Zachek

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Craig Kanugh

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Hyunjung Kim

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Jennifer J Laffin

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Josephine M Harter

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Kari B Wisinski

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Lauren M Zasadil

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P2860

The advantages and disadvantages of being polyploid

Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis

CARM1 methylates chromatin remodeling factor BAF155 to enhance tumor progression and metastasis

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure

Endoreplication cell cycles: more for less

From polyploidy to aneuploidy, genome instability and cancer

APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice.

Abnormal cytokinesis in cells deficient in the breast cancer susceptibility protein BRCA2

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

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48-59

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scholarly article

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10.1158/1535-7163.MCT-15-0527

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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Robert F Lera

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2015-11-19T00:00:00Z

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26586723

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P932

4707107

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Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer

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P2860

P2860

Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932