Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
about
KRAS Mutant Pancreatic Cancer: No Lone Path to an Effective TreatmentGenetics and biology of pancreatic ductal adenocarcinomaTherapeutic Targeting of AutophagyAutophagy-Dependent Secretion: Contribution to Tumor ProgressionAutophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumorsCytotoxic Indole Alkaloid 3α-Acetonyltabersonine Induces Glioblastoma Apoptosis via Inhibition of DNA Damage Repair.Choose and Use Your Chemical Probe Wisely to Explore Cancer Biology.Nanomedicine strategies to overcome the pathophysiological barriers of pancreatic cancer.Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62Mechanisms of Selective Autophagy in Normal Physiology and CancerAutophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells.Recent insights into the function of autophagy in cancer.Autophagy-dependent danger signaling and adaptive immunity to poorly immunogenic tumors.Lysosomotropism depends on glucose: a chloroquine resistance mechanismChloroquine-Modified Hydroxyethyl Starch as a Polymeric Drug for Cancer Therapy.Targeting metabolic reprogramming in KRAS-driven cancers.NF-κB Signaling Activation Induced by Chloroquine Requires Autophagosome, p62 Protein, and c-Jun N-terminal Kinase (JNK) Signaling and Promotes Tumor Cell Resistance.Non-cell-autonomous Effects of Autophagy Inhibition in Tumor Cells Promote Growth of Drug-resistant Cells.Molecular definitions of autophagy and related processes.Autophagy is required for cell survival under L-asparaginase-induced metabolic stress in acute lymphoblastic leukemia cells.Autophagy is not uniformly cytoprotective: a personalized medicine approach for autophagy inhibition as a therapeutic strategy in non-small cell lung cancer.Molecular Pathways Controlling Autophagy in Pancreatic Cancer.Autophagy, Inflammation, and Immunity: A Troika Governing Cancer and Its Treatment.The interplay between autophagy and tumorigenesis: exploiting autophagy as a means of anticancer therapy.Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles.Autophagy in natural and therapy-driven anticancer immunosurveillance.Assays to Monitor Autophagy Progression in Cell Cultures.The Challenge of Developing Autophagy Inhibition as a Therapeutic Strategy.Autophagy and Inflammatory Response in the Tumor Microenvironment.ATG7 promotes the tumorigenesis of lung cancer but might be dispensable for prognosis predication: a clinicopathologic studyALDH1A1 and HLTF modulate the activity of lysosomal autophagy inhibitors in cancer cells.Synthesis and Evaluation of Chloroquine-Containing DMAEMA Copolymers as Efficient Anti-miRNA Delivery Vectors with Improved Endosomal Escape and Antimigratory Activity in Cancer Cells.Targeting autophagy in cancer.Autophagy is dispensable for Kmt2a/Mll-Mllt3/Af9 AML maintenance and anti-leukemic effect of chloroquine.Polymeric chloroquine as an inhibitor of cancer cell migration and experimental lung metastasis.Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer.N-(1-Benzyl-3,5-dimethyl-1H-pyrazol-4-yl)benzamides: Antiproliferative Activity and Effects on mTORC1 and Autophagy.Inhibition of autophagy initiation potentiates chemosensitivity in mesothelioma.Repurposing Drugs in Oncology (ReDO)-chloroquine and hydroxychloroquine as anti-cancer agents.Targeting the Lysosome for Cancer Therapy.
P2860
Q26751520-7401AA48-4B60-4306-8CAB-44D132C253A9Q26765438-F5C3BC4E-195E-40A3-9044-5527705D0558Q28078117-06CBEE2E-44E8-4D77-A7C8-634B5B4E8F47Q28078649-4615257D-AA64-4562-A073-563707236B40Q28468571-BD4B1B70-37A5-4B99-92D6-E36A223651A2Q33744717-F4C6DC4C-87A6-4858-883E-1000783F896AQ33906319-378CC500-F5AB-4F33-B082-4FB719D431C9Q34537580-EF770B72-31DC-49B5-871D-0387EC1C9346Q36063007-5FCC2F60-4CB0-47EE-A145-C7DF976605CEQ36840116-E132F2FC-6D31-44C5-B231-C95243234199Q37212988-C13CB5AA-A968-47B7-BC33-D9BF3CE7B6E4Q37343004-E86C0148-4AF7-47B0-AF55-4254D67FB549Q37701461-F50FC8C8-7A4C-49E3-9A7F-CA6185914E0BQ38610330-3F2255A9-68E3-4540-BA03-03AB0BE73D6FQ38657644-EDA53EC8-E523-4587-A083-DE0E4C8238B4Q38710288-72C96F51-F717-47DB-A0C5-959418F8FDBFQ38721544-8F1B5A2B-3851-452E-9E80-241171F8CBD6Q38726186-548597C0-B7DA-45B0-895E-C7699A2DE545Q38735356-C6E6BAD6-553F-4BB6-9833-109F7764319DQ38739170-8B478F1D-0738-4CF0-875B-1A51649A7F11Q38868651-C05FEEF8-B905-41E7-94E3-4CC2C1998062Q38895232-ECFCEEF4-1F78-4348-86F8-4BF026F8830AQ38897741-B81CF2AC-ABAD-4DE0-9C14-EB8ABD8076BCQ39278658-73647BD8-9729-49DF-B19D-E52E2C2D60A5Q39321120-C2A99537-8B27-421B-8B4C-27606703EFEEQ39361915-F9908A79-2D0A-47F2-8D11-9BA4B8AF830FQ39420743-59DD2E5E-9FE9-4B1B-A206-9A6DB5F917FFQ41318193-15A785A9-F0E1-4947-93DC-ACC7D19A8B1BQ41660244-075E92CA-8501-41EB-8DA5-D4BAABBFEE72Q41753200-7C58B47F-6E35-40CF-85B4-43DAD68CE68EQ41911805-EAC7CF43-655D-4629-99E5-8A8FBC1184E8Q41912199-F0F51FC1-9D1C-494A-B896-D1F9C40AC21FQ41912265-59C23D16-BA43-47F8-854E-645B1FE207F3Q41913197-D2062247-7A0C-4AB1-9942-B9CF7B1C98C0Q41914534-24AD1668-D0DD-41A6-B0D4-BA70B9CF63B2Q42328292-65381CFB-C6A3-4485-BC5E-DF36DEC57333Q42504508-41BC7A27-B157-48C3-AE45-C25C0A3AE9AEQ46044385-40B6A993-2E37-4231-BE43-4D0E0ECE2762Q47162451-16BF940A-6DE4-45BC-B1AD-612080BCBFA0Q47447521-C640DE88-0B1B-44F7-82FC-D3E97321A1C8
P2860
Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
@ast
Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
@en
type
label
Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
@ast
Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
@en
prefLabel
Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
@ast
Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
@en
P2093
P2860
P356
P1476
Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
@en
P2093
Beat Nyfeler
Christina H Eng
Diane Tkach
Elizabeth Frias
Elizabeth George
Gregory McAllister
Gregory R Hoffman
Judy Lucas
Kevin Bray
Leon O Murphy
P2860
P304
P356
10.1073/PNAS.1515617113
P407
P577
2015-12-17T00:00:00Z