Sequential phosphorylation of smoothened transduces graded hedgehog signaling.
about
Translational regulation of the DOUBLETIME/CKIδ/ε kinase by LARK contributes to circadian period modulationIn vivo RNAi screen reveals neddylation genes as novel regulators of Hedgehog signalingSelective identification of hedgehog pathway antagonists by direct analysis of smoothened ciliary translocation.Essential roles of the Tap42-regulated protein phosphatase 2A (PP2A) family in wing imaginal disc development of Drosophila melanogaster.The ubiquitin E3 ligase NOSIP modulates protein phosphatase 2A activity in craniofacial development.A broadly conserved g-protein-coupled receptor kinase phosphorylation mechanism controls Drosophila smoothened activity.Hedgehog secretion and signal transduction in vertebrates.Hedgehog induces formation of PKA-Smoothened complexes to promote Smoothened phosphorylation and pathway activation.A targeted in vivo RNAi screen reveals deubiquitinases as new regulators of Notch signaling.Hh-induced Smoothened conformational switch is mediated by differential phosphorylation at its C-terminal tail in a dose- and position-dependent manner.Smoothened regulation in response to Hedgehog stimulation.Genetic interaction screens identify a role for hedgehog signaling in Drosophila border cell migration.Drosophila Condensin II subunit Chromosome-associated protein D3 regulates cell fate determination through non-cell-autonomous signaling.The exon junction complex regulates the splicing of cell polarity gene dlg1 to control Wingless signaling in development.A computation using mutually exclusive processing is sufficient to identify specific Hedgehog signaling components.Ubpy controls the stability of the ESCRT-0 subunit Hrs in development.Toward a systems-level understanding of the Hedgehog signaling pathway: defining the complex, robust, and fragile.The Hedgehog signal transduction network.Regulation of Hedgehog Signalling Inside and Outside the Cell.Hedgehog signalling is required for cell survival in Drosophila wing pouch cellsThe emerging roles of phosphatases in Hedgehog pathway.The PPFIA1-PP2A protein complex promotes trafficking of Kif7 to the ciliary tip and Hedgehog signaling.The complexities of G-protein-coupled receptor kinase function in Hedgehog signaling.A genetic mosaic screen identifies genes modulating Notch signaling in Drosophila
P2860
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P248
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P2860
Sequential phosphorylation of smoothened transduces graded hedgehog signaling.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Sequential phosphorylation of smoothened transduces graded hedgehog signaling.
@ast
Sequential phosphorylation of smoothened transduces graded hedgehog signaling.
@en
type
label
Sequential phosphorylation of smoothened transduces graded hedgehog signaling.
@ast
Sequential phosphorylation of smoothened transduces graded hedgehog signaling.
@en
prefLabel
Sequential phosphorylation of smoothened transduces graded hedgehog signaling.
@ast
Sequential phosphorylation of smoothened transduces graded hedgehog signaling.
@en
P2093
P2860
P1433
P1476
Sequential phosphorylation of smoothened transduces graded hedgehog signaling
@en
P2093
Adam M Schoen
Alan Jian Zhu
Andrew P Michelson
Jason K Ospina
Junzheng Zhang
P2860
P356
10.1126/SCISIGNAL.2001747
P50
P577
2011-07-05T00:00:00Z