mRNAs containing the histone 3' stem-loop are degraded primarily by decapping mediated by oligouridylation of the 3' end.
about
Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAsSurprises in the 3'-end: 'U' can decide too!Proteins involved in the degradation of cytoplasmic mRNA in the major eukaryotic model systemsA deep learning framework for modeling structural features of RNA-binding protein targets.The mRNP remodeling mediated by UPF1 promotes rapid degradation of replication-dependent histone mRNA.Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes.Uridylation by TUT4 and TUT7 marks mRNA for degradation.Deep sequencing shows multiple oligouridylations are required for 3' to 5' degradation of histone mRNAs on polyribosomesEnD-Seq and AppEnD: sequencing 3' ends to identify nontemplated tails and degradation intermediates.Oligoadenylation of 3' decay intermediates promotes cytoplasmic mRNA degradation in Drosophila cells.Two-headed tetraphosphate cap analogs are inhibitors of the Dcp1/2 RNA decapping complex.Signaling pathways that control mRNA turnover.Lsm proteins and Hfq: Life at the 3' endThe nucleic acid-binding domain and translational repression activity of a Xenopus terminal uridylyl transferase.A genome-wide RNAi screen reveals that mRNA decapping restricts bunyaviral replication by limiting the pools of Dcp2-accessible targets for cap-snatchingTUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAsUridylation and adenylation of RNAs.Molecular basis for cytoplasmic RNA surveillance by uridylation-triggered decay in Drosophila.Use of Mature miRNA Strand Selection in miRNAs Families in Cervical Cancer Development.Potential therapeutic applications of RNA cap analogs.Degradation of oligouridylated histone mRNAs: see UUUUU and goodbye.Synthetic mRNA: Production, Introduction into Cells, and Physiological Consequences.The C-terminal extension of Lsm4 interacts directly with the 3' end of the histone mRNP and is required for efficient histone mRNA degradation.RNA uridylation: a key posttranscriptional modification shaping the coding and noncoding transcriptome.TUT7 catalyzes the uridylation of the 3' end for rapid degradation of histone mRNA.bicaudal-C is required for the formation of anterior neurogenic ectoderm in the sea urchin embryo.Synthetic mRNA with Superior Properties that Mimics the Intracellular Fates of Natural Histone mRNA.
P2860
Q24338738-F169DD4D-7F68-4D7F-949A-18463C69DED2Q26800072-C6B509CC-AF00-4CCA-9AE9-104A5899AD3DQ26864165-44557128-69E1-4946-90B7-A3A56717E0EDQ30390089-CAC01AE7-8BFC-4EE5-9AC1-318500D2CC97Q34044351-D9AA51B6-9FBB-4913-BACF-E15A793E7AB1Q34249684-A8DACDC3-60B3-494C-A559-C135E4CF870AQ34452309-84A80EF9-9FA9-4749-BE24-C112C459624BQ35127551-7BC29008-B4C6-4A7D-A7BB-E0C7771E5021Q35773299-D2F82EC7-2485-4091-92AA-B0792E2D17ABQ35898390-CD38A762-3439-4481-A52A-C14FC99977C6Q35908793-235D9AA1-F128-48EB-B686-B9A81883A63CQ36988764-85047C31-C77C-4A80-9EF4-4DBC0E9D6015Q37009111-F63C85B0-024D-4624-BAF0-95C10BA057A0Q37012548-A23D7476-915F-46E6-9071-3886E319FCAFQ37019225-A96D1524-D080-442D-9694-BC0327267B4CQ37348869-82332879-0B9F-4A76-84A2-4C4B9B89D405Q37385261-39F4ED74-A280-4482-BB23-72AC164769A9Q37414035-F10B0B10-6662-465F-BAD0-ECAA20845F70Q37690967-C2DE7EE9-9EAE-4C23-A50A-45BD618740ADQ38116576-3ADA3CF6-8A18-4CFF-A4F5-2E0C2990AB32Q38201414-DC550C03-2FFF-4530-BB88-F67DC17AE8E7Q40654970-C3713473-B363-4663-875D-4DDD0213CDD2Q41841894-3841FF78-758C-45FF-A295-ADE1E9DC893AQ41923088-9C38E2F8-D645-414C-98D2-2978E5CB7A82Q42704832-7175302E-BBE4-44BE-8C4E-5FAF5416D5DFQ42969865-51FB79D4-0BDB-41FA-93F0-7EA9FD7F2D1CQ51313265-B97F4DC7-338D-4AEA-9489-94479F37F9AA
P2860
mRNAs containing the histone 3' stem-loop are degraded primarily by decapping mediated by oligouridylation of the 3' end.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
mRNAs containing the histone 3 ...... ligouridylation of the 3' end.
@ast
mRNAs containing the histone 3 ...... ligouridylation of the 3' end.
@en
type
label
mRNAs containing the histone 3 ...... ligouridylation of the 3' end.
@ast
mRNAs containing the histone 3 ...... ligouridylation of the 3' end.
@en
prefLabel
mRNAs containing the histone 3 ...... ligouridylation of the 3' end.
@ast
mRNAs containing the histone 3 ...... ligouridylation of the 3' end.
@en
P2093
P2860
P50
P356
P1433
P1476
mRNAs containing the histone 3 ...... oligouridylation of the 3' end
@en
P2093
Edward Darzynkiewicz
Michael K Slevin
Robert E Rhoads
Sergey V Slepenkov
William F Marzluff
P2860
P356
10.1261/RNA.034470.112
P407
P577
2012-11-27T00:00:00Z