The Ets transcription factor Elf5 specifies mammary alveolar cell fate. - Test2 - elhamkhani - TriplyDB

The Ets transcription factor Elf5 specifies mammary alveolar cell fate.

The Ets transcription factor Elf5 specifies mammary alveolar cell fate.

http://www.wikidata.org/entity/Q36484174

about

Developmental signaling pathways regulating mammary stem cells and contributing to the etiology of triple-negative breast cancer Form and function: how estrogen and progesterone regulate the mammary epithelial hierarchy The mammary stem cell hierarchy: a looking glass into heterogeneous breast cancer landscapes Mammary stem cells and the differentiation hierarchy: current status and perspectives Luminal progenitors restrict their lineage potential during mammary gland development Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland Essential role for a novel population of binucleated mammary epithelial cells in lactation.Epigenetic modifications unlock the milk protein gene loci during mouse mammary gland development and differentiation Transcriptional repressor Tbx3 is required for the hormone-sensing cell lineage in mammary epithelium ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells D-type Cyclins are important downstream effectors of cytokine signaling that regulate the proliferation of normal and neoplastic mammary epithelial cells.The Stat6-regulated KRAB domain zinc finger protein Zfp157 regulates the balance of lineages in mammary glands and compensates for loss of Gata-3 Loss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formation Pregnancy-induced noncoding RNA (PINC) associates with polycomb repressive complex 2 and regulates mammary epithelial differentiation Development of mammary luminal progenitor cells is controlled by the transcription factor STAT5A Elf5 inhibits the epithelial–mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2 ELF5 isoform expression is tissue-specific and significantly altered in cancer.Genome-wide search identifies Ccnd2 as a direct transcriptional target of Elf5 in mouse mammary gland.Transcript profiling of Elf5+/- mammary glands during pregnancy identifies novel targets of Elf5.Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate.Association and haplotype analyses of positional candidate genes in five genomic regions linked to scrotal hernia in commercial pig lines.Prolactin cooperates with loss of p53 to promote claudin-low mammary carcinomas RUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland.Minireview: prolactin regulation of adult stem cells The antiproliferative effects of progestins in T47D breast cancer cells are tempered by progestin induction of the ETS transcription factor Elf5.The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy.The bHLH/PAS transcription factor singleminded 2s promotes mammary gland lactogenic differentiation Tip30 controls differentiation of murine mammary luminal progenitor to estrogen receptor-positive luminal cell through regulating FoxA1 expression Phenotypic and functional characterisation of the luminal cell hierarchy of the mammary gland.Aberrant Proliferation of Differentiating Alveolar Cells Induces Hyperplasia in Resting Mammary Glands of SV40-TAg Transgenic Mice Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways The co-factor of LIM domains (CLIM/LDB/NLI) maintains basal mammary epithelial stem cells and promotes breast tumorigenesis.Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer The mammary cellular hierarchy and breast cancer.CCAAT/enhancer binding protein beta regulates stem cell activity and specifies luminal cell fate in the mammary gland.The epigenetic landscape of mammary gland development and functional differentiation.ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer.The ETS family of oncogenic transcription factors in solid tumours.Murine mammary epithelial stem cells: discovery, function, and current status.The STAT5-regulated miR-193b locus restrains mammary stem and progenitor cell activity and alveolar differentiation.

P2860

Q26766266-B58F3993-4CF6-4DCC-A6F3-05AD661D855D Q26799290-6685544B-2C0B-4354-A22B-FDBBDF100D8E Q26799993-0E0C0041-F6B1-413C-B479-A71149BEB18A Q27003345-218D7D93-8E5A-4E72-95F2-225FCF18D53F Q27312866-8910DFCE-CA94-49CA-92F9-0EA43B2F626A Q27315980-CD189C11-AAD0-4A84-9000-AF5A886B35F0 Q27318783-30A1000D-B347-4DB7-A472-27B020DA78D9 Q27322605-0BA69658-9D18-41F4-91B8-A71FD451E115 Q27335408-8887661C-364D-43D8-952F-F4DE664D88ED Q27345430-DD08B066-EAD4-40E8-BB70-434FEC945E9C Q27690967-2501A7A0-E1D4-4DCC-BF96-28D900AD0219 Q28505725-D6E16597-785D-400E-A80D-0A2A98186932 Q28508528-9878DC38-F6BE-42D4-9463-D79D325E9459 Q28512630-45E9A394-E0C4-4E30-B062-1C9D4F05B5FA Q28585680-F99BF8C6-B72A-4792-B224-2873639E2234 Q29042375-B8F75185-968E-4CFF-B190-C12C56FA3CDC Q30383247-E9EA261E-0E4D-4790-AD75-131C19F34DDF Q30989290-BB8BF14B-CEA9-4606-AD3A-82898A39DB5C Q30990417-4A117AEB-E79C-4BF5-A269-037BA1D73E78 Q33390756-286BC7BE-94BF-44DC-ADFD-C612B9138BE8 Q33418306-A6E8D8B9-AE7F-4E79-B686-45424CD6FB8B Q33555787-50566B57-FC90-450C-83B8-7284E90383F7 Q33555996-75065B61-0DD9-4468-AF6C-6E155F3572A1 Q33631708-AF11E82A-99EF-47A6-AE2C-CC73ADC2B15A Q33637475-AD4FF0FE-CEDD-4A94-957B-ED6DD7276F4B Q33660069-6F9C9C9C-A73A-4B85-8A1D-5445701619F7 Q33710892-660C0AF4-CE1E-41A5-90D7-628CF3FDC9C4 Q33720151-AFA184D9-4FFD-4DF3-9A46-A5DD6F5593D6 Q33739278-05EABA0B-AAB5-4E01-82D9-80A3F7B8A82B Q33809166-6259162B-0EFB-49E8-A9EC-EEAB2E79127F Q33889518-852FEAD8-5507-417E-8DC0-DACFEA80C0A2 Q33981658-613E4BDB-D318-481D-B5C8-5689B570B3D0 Q34258504-0EAB577E-B07F-4E8F-A3ED-4D4B545FBD15 Q34396558-943D757F-8E33-4985-94D7-F7BB11F1DFA4 Q34425850-48C28432-8B45-42D9-B8C4-26EB0F56EB92 Q34425899-948C08FF-FF37-4D63-92A0-4DB90DCD5ADD Q34539617-81635905-52E0-46F5-8F64-E18E8A144454 Q34555986-8B11FD55-546A-4D9C-8C6E-B3499361132F Q34576381-858F3FBA-3FDE-49FC-9DE9-940325F6FD0D Q34614261-F2BA6D81-0EBC-4EAA-BCE4-A430E1218A54

P2860

The Ets transcription factor Elf5 specifies mammary alveolar cell fate.

http://www.wikidata.org/entity/Q36484174

description

2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年学术文章

@wuu

2008年学术文章

@zh-cn

2008年学术文章

@zh-hans

2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

@yue

2008年學術文章

@zh

2008年學術文章

@zh-hant

name

The Ets transcription factor Elf5 specifies mammary alveolar cell fate.

@ast

The Ets transcription factor Elf5 specifies mammary alveolar cell fate.

@en

type

label

The Ets transcription factor Elf5 specifies mammary alveolar cell fate.

@ast

The Ets transcription factor Elf5 specifies mammary alveolar cell fate.

@en

prefLabel

The Ets transcription factor Elf5 specifies mammary alveolar cell fate.

@ast

The Ets transcription factor Elf5 specifies mammary alveolar cell fate.

@en

P1433

Q36484174-78DB1D50-E1B4-483A-BC01-7506187827B0

P1476

Q36484174-6A7BA993-D862-466F-8FD6-A02F66463331

P2093

Q36484174-133648BB-66F0-4E01-A42A-DB190ABB3FD7

Q36484174-28F3D94D-D1B2-4B52-89AE-479BCFA16CEB

Q36484174-3495426F-6720-4A9A-A8F2-19FD79CB2F13

Q36484174-4E15D0F4-71AD-4453-87A1-6A19395646E1

Q36484174-545DF1A7-A1BA-42BF-887C-F4541B5E3838

Q36484174-574C57D8-855A-40BB-BCC1-EC4B3D6C3B5E

Q36484174-658BA80C-5272-4797-9387-A97C683188EB

Q36484174-72B2C16C-6821-4DC7-8EF3-9AAA228DC9F3

Q36484174-7FC83765-7EFE-47B5-A44A-5C89F877587F

Q36484174-A2F14DEC-8D91-4B6A-833B-3FF1E3F42B0E

P2860

Q36484174-006C93A1-E5A8-47A6-82FC-818ADB5E359A

Q36484174-11CAE3D1-184D-43A8-A29E-EFF3EF43AB99

Q36484174-1A16A0AE-175D-4190-B2F4-F21430B20F95

Q36484174-2A55E57A-DEAB-4BA1-A64D-E5ED8AB5C7B7

Q36484174-34916544-1FAA-40E8-9B0C-4D7F59E8FB80

Q36484174-6023E452-B3A2-4227-B323-EB4BF9E51072

Q36484174-7695A993-7AA8-43BF-AB3C-279F746AA22B

Q36484174-8101B574-0FA2-47A1-BE6C-37B75A284326

Q36484174-8CC334F3-F43C-4156-8C9F-21CEF4316365

Q36484174-8EA0BFCA-2F64-4333-9754-5D5C494D2920

P304

Q36484174-1F5A352B-8673-4002-8FD6-59943F1E2D3E

P31

Q36484174-6F41D884-889D-41EF-A902-F5FCBC8F5728

P356

Q36484174-A07E8794-58DA-4E87-A563-C999047B8012

P433

Q36484174-F6399196-BFAD-432D-80D3-66D68F02238B

P478

Q36484174-C23B7066-A0DF-4930-8494-E0E08054C501

P50

Q36484174-F3399DF1-CE2E-4EA7-9E44-8080E2CDBB9C

P577

Q36484174-80B62926-FB23-40CB-A747-8DCF05B3FD55

P5875

Q36484174-B710798E-5E77-4CFB-A7FA-ED15F506ABD8

P698

Q36484174-4CBF4895-8213-49E3-A14B-7FDF11D6A170

P932

Q36484174-8B6BEB8D-DDC0-4547-8F2A-9ED85DD2AF92

P356

P1433

Genes & Development

P1476

The Ets transcription factor Elf5 specifies mammary alveolar cell fate.

@en

P2093

Christopher J Ormandy

http://www.w3.org/2001/XMLSchema#string

Geoffrey J Lindeman

http://www.w3.org/2001/XMLSchema#string

Heidi N Hilton

http://www.w3.org/2001/XMLSchema#string

Jane E Visvader

http://www.w3.org/2001/XMLSchema#string

Katrina D Blazek

http://www.w3.org/2001/XMLSchema#string

Lewis A Chodosh

http://www.w3.org/2001/XMLSchema#string

Margaret Gardiner-Garden

http://www.w3.org/2001/XMLSchema#string

Marie-Liesse Asselin-Labat

http://www.w3.org/2001/XMLSchema#string

Matthew J Naylor

http://www.w3.org/2001/XMLSchema#string

Melanie A Pritchard

http://www.w3.org/2001/XMLSchema#string

P2860

A novel transcription factor, ELF5, belongs to the ELF subfamily of ETS genes and maps to human chromosome 11p13-15, a region subject to LOH and rearrangement in human carcinoma cell lines

GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland

Loss of the extraembryonic ectoderm in Elf5 mutants leads to defects in embryonic patterning

RAG-1-deficient mice have no mature B and T lymphocytes

Socs2 and elf5 mediate prolactin-induced mammary gland development

Generation of a functional mammary gland from a single stem cell

Purification and unique properties of mammary epithelial stem cells

Elf5 is essential for early embryogenesis and mammary gland development during pregnancy and lactation.

Characterization of ESE-2, a novel ESE-1-related Ets transcription factor that is restricted to glandular epithelium and differentiated keratinocytes.

The Elf group of Ets-related transcription factors. ELF3 and ELF5.

P304

581-586

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1101/GAD.1614608

http://www.w3.org/2001/XMLSchema#string

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

22

http://www.w3.org/2001/XMLSchema#string

P50

P577

2008-03-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5536718

http://www.w3.org/2001/XMLSchema#string

P698

18316476

http://www.w3.org/2001/XMLSchema#string

P932

2259028

http://www.w3.org/2001/XMLSchema#string