Evolutionary paths to antibiotic resistance under dynamically sustained drug selection
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Quantifying the adaptive potential of an antibiotic resistance enzymeReplaying the tape of life in the twenty-first centuryThe extended regulatory networks of SXT/R391 integrative and conjugative elements and IncA/C conjugative plasmidsElucidating the molecular architecture of adaptation via evolve and resequence experimentsSpatiotemporal microbial evolution on antibiotic landscapesEvolutionary rescue: linking theory for conservation and medicineMicroscale insights into pneumococcal antibiotic mutant selection windowsWithin-host evolution of bacterial pathogens.Antibiotic resistance in the wild: an eco-evolutionary perspectiveIn vivo continuous directed evolutionCoordinated Evolution of Influenza A Surface ProteinsQuantifying the Determinants of Evolutionary Dynamics Leading to Drug ResistancePopulation Density Modulates Drug Inhibition and Gives Rise to Potential Bistability of Treatment Outcomes for Bacterial InfectionsTackling Drug Resistant Infection Outbreaks of Global Pandemic Escherichia coli ST131 Using Evolutionary and Epidemiological Genomics.Residue mutations and their impact on protein structure and function: detecting beneficial and pathogenic changes.Bacterial growth and adaptation in microdroplet chemostats.Origin of robustness in generating drug-resistant malaria parasitesWithin-Host Evolution of Burkholderia pseudomallei during Chronic Infection of Seven Australasian Cystic Fibrosis Patients.A scalable metabolite supplementation strategy against antibiotic resistant pathogen Chromobacterium violaceum induced by NAD+/NADH+ imbalance.Adaptive Laboratory Evolution of Antibiotic Resistance Using Different Selection Regimes Lead to Similar Phenotypes and Genotypes.Evolved osmotolerant Escherichia coli mutants frequently exhibit defective N-acetylglucosamine catabolism and point mutations in cell shape-regulating protein MreB.Time-programmable drug dosing allows the manipulation, suppression and reversal of antibiotic drug resistance in vitroCauses of molecular convergence and parallelism in protein evolution.Genomics of rapid adaptation to antibiotics: convergent evolution and scalable sequence amplificationMultidrug evolutionary strategies to reverse antibiotic resistance.Whole-genome sequencing to control antimicrobial resistanceShort-term differential adaptation to anaerobic stress via genomic mutations by Escherichia coli strains K-12 and B lacking alcohol dehydrogenase.Antibiotics and the gut microbiota.Alternating antibiotic treatments constrain evolutionary paths to multidrug resistancePrediction of antibiotic resistance by gene expression profiles.Systems mapping of HIV-1 infection.The effect of bacterial recombination on adaptation on fitness landscapes with limited peak accessibilityReplaying the tape of life: quantification of the predictability of evolution.The evolutionary history of amino acid variations mediating increased resistance of S. aureus identifies reversion mutations in metabolic regulatorsEvolution after introduction of a novel metabolic pathway consistently leads to restoration of wild-type physiology.Genomic analysis reveals distinct concentration-dependent evolutionary trajectories for antibiotic resistance in Escherichia coli.Mutations in global regulators lead to metabolic selection during adaptation to complex environments.Insights into mechanisms and proteomic characterisation of Pseudomonas aeruginosa adaptation to a novel antimicrobial substanceGWAMAR: genome-wide assessment of mutations associated with drug resistance in bacteria.A low cost, customizable turbidostat for use in synthetic circuit characterization.
P2860
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P2860
Evolutionary paths to antibiotic resistance under dynamically sustained drug selection
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Evolutionary paths to antibiotic resistance under dynamically sustained drug selection
@ast
Evolutionary paths to antibiotic resistance under dynamically sustained drug selection
@en
type
label
Evolutionary paths to antibiotic resistance under dynamically sustained drug selection
@ast
Evolutionary paths to antibiotic resistance under dynamically sustained drug selection
@en
prefLabel
Evolutionary paths to antibiotic resistance under dynamically sustained drug selection
@ast
Evolutionary paths to antibiotic resistance under dynamically sustained drug selection
@en
P2093
P2860
P356
P1433
P1476
Evolutionary paths to antibiotic resistance under dynamically sustained drug selection
@en
P2093
Adrian Veres
Daniel L Hartl
Erdal Toprak
Jean-Baptiste Michel
Roy Kishony
P2860
P2888
P304
P356
10.1038/NG.1034
P407
P50
P577
2011-12-18T00:00:00Z