Role of the GATA family of transcription factors in endocrine development, function, and disease - Test2 - elhamkhani - TriplyDB

Role of the GATA family of transcription factors in endocrine development, function, and disease

Role of the GATA family of transcription factors in endocrine development, function, and disease

http://www.wikidata.org/entity/Q36512426

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Zinc finger protein, multitype 1, suppresses human Th2 development via downregulation of IL-4 The steroid receptor RNA activator protein is recruited to promoter regions and acts as a transcriptional repressor Loss-of-function mutation in GATA4 causes anomalies of human testicular development Toying with fate: Redirecting the differentiation of adrenocortical progenitor cells into gonadal-like tissue An Ebox element in the proximal Gata4 promoter is required for Gata4 expression in vivo Mammalian sex determination—insights from humans and mice.Molecular mechanism of monoamine oxidase A gene regulation under inflammation and ischemia-like conditions: key roles of the transcription factors GATA2, Sp1 and TBP GATA4 regulates Sertoli cell function and fertility in adult male mice GATA6 is a crucial regulator of Shh in the limb bud Decreased expression of synapse-related genes and loss of synapses in major depressive disorder GATA transcription factors in vertebrates: evolutionary, structural and functional interplay.Loss of GATA-6 and GATA-4 in granulosa cells blocks folliculogenesis, ovulation, and follicle stimulating hormone receptor expression leading to female infertility.Genomic androgen receptor-occupied regions with different functions, defined by histone acetylation, coregulators and transcriptional capacity PIAS1 is a GATA4 SUMO ligase that regulates GATA4-dependent intestinal promoters independent of SUMO ligase activity and GATA4 sumoylation.Evolutionary conservation of zinc finger transcription factor binding sites in promoters of genes co-expressed with WT1 in prostate cancer Conserved usage of alternative 5' untranslated exons of the GATA4 gene Review paper: origin and molecular pathology of adrenocortical neoplasms GATA2-induced silencing and LIM-homeodomain protein-induced activation are mediated by a bi-functional response element in the rat GnRH receptor gene.FSH and its second messenger cAMP stimulate the transcription of human anti-Müllerian hormone in cultured granulosa cells.Toxicogenomic analysis of exposure to TCDD, PCB126 and PCB153: identification of genomic biomarkers of exposure to AhR ligands Blood-testis barrier and spermatogenesis: lessons from genetically-modified mice.ToppCluster: a multiple gene list feature analyzer for comparative enrichment clustering and network-based dissection of biological systems.Molecular basis of crosstalk between oncogenic Ras and the master regulator of hematopoiesis GATA-2 Expression of Transcription Factor GATA-6 in Alveolar Epithelial Cells Is Linked to Neonatal Lung Disease.GATA depletion impacts insulin-like growth factor 1 mRNA and protein levels in luteinizing porcine granulosa cells Pathway-based analysis of GWAs data identifies association of sex determination genes with susceptibility to testicular germ cell tumors.GATA4 negatively regulates osteoblast differentiation by downregulation of Runx2.Endothelin-1 gene regulation STARD6 is expressed in steroidogenic cells of the ovary and can enhance de novo steroidogenesis.Absent, small or homeotic 2-like protein (ASH2L) enhances the transcription of the estrogen receptor α gene through GATA-binding protein 3 (GATA3).GATA4 deficiency impairs ovarian function in adult mice.The role of miR-206 in the epidermal growth factor (EGF) induced repression of estrogen receptor-alpha (ERalpha) signaling and a luminal phenotype in MCF-7 breast cancer cells.GATA4 regulates estrogen receptor-alpha-mediated osteoblast transcription.Combined loss of the GATA4 and GATA6 transcription factors in male mice disrupts testicular development and confers adrenal-like function in the testes.GATA4 is a key regulator of steroidogenesis and glycolysis in mouse Leydig cells.Simultaneous gene deletion of gata4 and gata6 leads to early disruption of follicular development and germ cell loss in the murine ovary.Adrenal Development in Mice Requires GATA4 and GATA6 Transcription Factors DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients.DNA demethylation-dependent AR recruitment and GATA factors drive Rhox5 homeobox gene transcription in the epididymis.GATA4 is a critical regulator of gonadectomy-induced adrenocortical tumorigenesis in mice.

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Role of the GATA family of transcription factors in endocrine development, function, and disease

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2008 nî lūn-bûn

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Role of the GATA family of tra ...... lopment, function, and disease

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Role of the GATA family of tra ...... lopment, function, and disease

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Role of the GATA family of tra ...... lopment, function, and disease

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Role of the GATA family of tra ...... lopment, function, and disease

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Role of the GATA family of tra ...... lopment, function, and disease

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Molecular Endocrinology

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Role of the GATA family of tra ...... lopment, function, and disease

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Markku Heikinheimo

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Mikko Anttonen

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Robert S Viger

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Séverine Mazaud Guittot

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P2860

A mutation in the gene encoding steroidogenic factor-1 causes XY sex reversal and adrenal failure in humans

hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activation

Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1

GATA3 haplo-insufficiency causes human HDR syndrome

GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5

Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1

GATA-4 and GATA-6 modulate tissue-specific transcription of the human gene for P450c17 by direct interaction with Sp1

The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors.

GATA-6 induces p21(Cip1) expression and G1 cell cycle arrest

Concerted regulation of the porcine steroidogenic acute regulatory protein gene promoter activity by follicle-stimulating hormone and insulin-like growth factor I in granulosa cells involves GATA-4 and CCAAT/enhancer binding protein beta

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781-798

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scholarly article

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10.1210/ME.2007-0513

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4

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22

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David B. Wilson

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2008-01-03T00:00:00Z

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5676356

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18174356

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2276466

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