The CCAN recruits CENP-A to the centromere and forms the structural core for kinetochore assembly. - Test2 - elhamkhani - TriplyDB

The CCAN recruits CENP-A to the centromere and forms the structural core for kinetochore assembly.

The CCAN recruits CENP-A to the centromere and forms the structural core for kinetochore assembly.

http://www.wikidata.org/entity/Q36525667

about

The pseudo GTPase CENP-M drives human kinetochore assembly The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling Kinetochore function is controlled by a phospho-dependent coexpansion of inner and outer components.CENP-C directs a structural transition of CENP-A nucleosomes mainly through sliding of DNA gyres The CENP-T/-W complex is a binding partner of the histone chaperone FACT.Structural insights into the role of the Chl4-Iml3 complex in kinetochore assembly A Dual Inhibitory Mechanism Sufficient to Maintain Cell-Cycle-Restricted CENP-A Assembly.Licensing of Centromeric Chromatin Assembly through the Mis18α-Mis18β Heterotetramer.The distinct functions of CENP-C and CENP-T/W in centromere propagation and function in Xenopus egg extracts.A cell-free CENP-A assembly system defines the chromatin requirements for centromere maintenance.Both tails and the centromere targeting domain of CENP-A are required for centromere establishment A two-step mechanism for epigenetic specification of centromere identity and function.The quantitative architecture of centromeric chromatin CAL1 is the Drosophila CENP-A assembly factor A new piece in the kinetochore jigsaw puzzle The kinetochore Histone H4 Lys 20 monomethylation of the CENP-A nucleosome is essential for kinetochore assembly.The centromere: chromatin foundation for the kinetochore machinery.The dynamics of signal amplification by macromolecular assemblies for the control of chromosome segregation Chromosome engineering allows the efficient isolation of vertebrate neocentromeres.Holocentromeres are dispersed point centromeres localized at transcription factor hotspots.The architecture of CCAN proteins creates a structural integrity to resist spindle forces and achieve proper Intrakinetochore stretch.Centromeric heterochromatin: the primordial segregation machine.The centromere: epigenetic control of chromosome segregation during mitosis DNA Sequence-Specific Binding of CENP-B Enhances the Fidelity of Human Centromere Function CENP-C is a blueprint for constitutive centromere-associated network assembly within human kinetochores A quantitative description of Ndc80 complex linkage to human kinetochores HJURP is involved in the expansion of centromeric chromatin.Dynamic changes in CCAN organization through CENP-C during cell-cycle progression.Stepwise unfolding supports a subunit model for vertebrate kinetochores Whole-proteome genetic analysis of dependencies in assembly of a vertebrate kinetochore.The CENP-L-N Complex Forms a Critical Node in an Integrated Meshwork of Interactions at the Centromere-Kinetochore Interface CENP-C and CENP-I are key connecting factors for kinetochore and CENP-A assembly RNAi pathway participates in chromosome segregation in mammalian cells Induced dicentric chromosome formation promotes genomic rearrangements and tumorigenesis.Genomic variation within alpha satellite DNA influences centromere location on human chromosomes with metastable epialleles.Acetylation of histone H4 lysine 5 and 12 is required for CENP-A deposition into centromeres.The centromeric nucleosome-like CENP-T-W-S-X complex induces positive supercoils into DNA.Molecular basis of outer kinetochore assembly on CENP-T.A CENP-S/X complex assembles at the centromere in S and G2 phases of the human cell cycle.

P2860

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P2860

The CCAN recruits CENP-A to the centromere and forms the structural core for kinetochore assembly.

http://www.wikidata.org/entity/Q36525667

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The CCAN recruits CENP-A to th ...... core for kinetochore assembly.

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The CCAN recruits CENP-A to th ...... core for kinetochore assembly.

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P2093

Kozo Takeuchi

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Tatsuo Fukagawa

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Tetsuya Hori

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Wei-Hao Shang

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P2860

Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis.

Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1

Induced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomes

CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold

The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation.

The conserved KMN network constitutes the core microtubule-binding site of the kinetochore

Centromere-specific assembly of CENP-a nucleosomes is mediated by HJURP.

HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres

CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore

CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate

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45-60

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10.1083/JCB.201210106

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1

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200

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234019811

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23277427

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3542802

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