Translating advances from the basic biology of aging into clinical application - Test2 - elhamkhani - TriplyDB

Translating advances from the basic biology of aging into clinical application

Translating advances from the basic biology of aging into clinical application

http://www.wikidata.org/entity/Q36528628

about

Building for the future: essential infrastructure for rodent ageing studies You're only as old as your arteries: translational strategies for preserving vascular endothelial function with aging Inorganic nitrite supplementation for healthy arterial aging Battery of behavioral tests in mice that models age-associated changes in human motor function.Reliability of a Frailty Index Based on the Clinical Assessment of Health Deficits in Male C57BL/6J Mice Implementation of longevity-promoting supplements and medications in public health practice: achievements, challenges and future perspectives Cognitive effects of cancer systemic therapy: implications for the care of older patients and survivors.The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice.Clinical strategies and animal models for developing senolytic agents.Translational geroscience: emphasizing function to achieve optimal longevity Gait Speed Predicts Incident Disability: A Pooled Analysis.Sodium nitrite supplementation improves motor function and skeletal muscle inflammatory profile in old male mice.Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity.Obesity and related consequences to ageing.Cognitive effects of cancer and its treatments at the intersection of aging: what do we know; what do we need to know?Life-long spontaneous exercise does not prolong lifespan but improves health span in mice.Substantial health and economic returns from delayed aging may warrant a new focus for medical research.Infrastructure and resources for an aging population: embracing complexity in translational research.Translational physiology: from molecules to public health.Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity.Has the Rate of Human Aging Already Been Modified?The Economic Promise of Delayed Aging.Articulating the Case for the Longevity Dividend.Translating the Science of Aging into Therapeutic Interventions.Physiological Aging: Links Among Adipose Tissue Dysfunction, Diabetes, and Frailty.Cellular Senescence: A Translational Perspective.Impact of early personal-history characteristics on the Pace of Aging: implications for clinical trials of therapies to slow aging and extend healthspan.Comparative Approaches to Understanding the Relation Between Aging and Physical Function.The Effect of Piceatannol from Passion Fruit (Passiflora edulis) Seeds on Metabolic Health in Humans.The Longitudinal Study of Aging in Human Young Adults: Knowledge Gaps and Research Agenda.Estimates of the Heritability of Human Longevity Are Substantially Inflated due to Assortative Mating Elevated serum IL-6 and adiponectin levels are associated with frailty and physical function in Chinese older adults

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Translating advances from the basic biology of aging into clinical application

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J.EXGER.2012.11.014

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Experimental Gerontology

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James L Kirkland

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Single-gene mutations and healthy ageing in mammals

Nonlinear multisystem physiological dysregulation associated with frailty in older women: implications for etiology and treatment

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Frailty in older adults: evidence for a phenotype

Leukocyte count as a predictor of cardiovascular events and mortality in postmenopausal women: the Women's Health Initiative Observational Study

Frailty and activation of the inflammation and coagulation systems with and without clinical comorbidities: results from the Cardiovascular Health Study

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

Phenotype of frailty: characterization in the women's health and aging studies

Rejuvenation of aged progenitor cells by exposure to a young systemic environment

C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus

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