The Achilles' heel of senescent cells: from transcriptome to senolytic drugs. - Test2 - elhamkhani - TriplyDB

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

http://www.wikidata.org/entity/Q34043405

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Building for the future: essential infrastructure for rodent ageing studies DNA Damage: A Main Determinant of Vascular Aging Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules Developing criteria for evaluation of geroprotectors as a key stage toward translation to the clinic Cellular Senescence as the Causal Nexus of Aging Healthy aging: The ultimate preventative medicine Cellular senescence in aging and age-related disease: from mechanisms to therapy Changes in Regenerative Capacity through Lifespan Cellular Senescence and the Biology of Aging, Disease, and Frailty DNA damage response (DDR) and senescence: shuttled inflamma-miRNAs on the stage of inflamm-aging Small molecule compounds that induce cellular senescence Systemic DNA damage responses in aging and diseases Aging and adipose tissue: potential interventions for diabetes and regenerative medicine Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells Mitochondria in the spotlight of aging and idiopathic pulmonary fibrosis Pathophysiology of Aortic Valve Stenosis: Is It Both Fibrocalcific and Sex Specific?Gaps in Aging Research as it Applies to Rheumatologic Clinical Care.Should we treat aging as a disease? The consequences and dangers of miscategorisation.Resveratrol sequentially induces replication and oxidative stresses to drive p53-CXCR2 mediated cellular senescence in cancer cells.A Novel Indication for Panobinostat as a Senolytic Drug in NSCLC and HNSCC.Cellular senescence drives age-dependent hepatic steatosis.New challenges of geriatric cardiology: from clinical to preclinical research Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice.Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age.Targeting senescent cells enhances adipogenesis and metabolic function in old age 17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization Senotherapy: growing old and staying young?Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity.Programmed cell death in aging.Stem cell aging in adult progeria.Discovery of piperlongumine as a potential novel lead for the development of senolytic agents.Cellular Senescence and Inflammatory Burden as Determinants of Mortality in Elderly People Until the Extreme old age Challenges and opportunities for stem cell therapy in patients with chronic kidney disease Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue.Satellite Cells in Muscular Dystrophy - Lost in Polarity.Pharmacological Strategies to Retard Cardiovascular Aging Anti-TNF-α treatment modulates SASP and SASP-related microRNAs in endothelial cells and in circulating angiogenic cells.

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P2860

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

http://www.wikidata.org/entity/Q34043405

description

2015 nî lūn-bûn

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2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2015 թվականի ապրիլին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

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The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

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The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

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The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

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The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

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The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

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The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

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The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

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The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

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The Achilles' heel of senescent cells: from transcriptome to senolytic drugs

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Adam C Gower

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Aditi U Gurkar

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Akaitz Dorronsoro

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Amira S Barghouthy

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Carolyn M Roos

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Debora Colangelo

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Diana C Navarro

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Gene B Hubbard

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Grace C Verzosa

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Heike Fuhrmann-Stroissnigg

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P2860

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Senescence of activated stellate cells limits liver fibrosis

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network.

Physiological consequences of defects in ERCC1-XPF DNA repair endonuclease

Lost in transcription: p21 repression, mechanisms, and consequences

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

ERCC1-XPF endonuclease facilitates DNA double-strand break repair

Ethanol promotes mammary tumor growth and angiogenesis: the involvement of chemoattractant factor MCP-1

Blinded by the Light: The Growing Complexity of p53

Cellular survival: a play in three Akts

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644-658

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10.1111/ACEL.12344

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4

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14

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Nathan K. LeBrasseur

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2015-04-22T00:00:00Z

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273385787

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25754370

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4531078

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