Role of prostaglandin receptor EP2 in the regulations of cancer cell proliferation, invasion, and inflammation.
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Eicosanoid pathway in colorectal cancer: Recent updatesFluid shear stress-induced osteoarthritis: roles of cyclooxygenase-2 and its metabolic products in inducing the expression of proinflammatory cytokines and matrix metalloproteinasesCanolol inhibits gastric tumors initiation and progression through COX-2/PGE2 pathway in K19-C2mE transgenic miceProstaglandin receptor EP2 in the crosshairs of anti-inflammation, anti-cancer, and neuroprotectionLead optimization studies of cinnamic amide EP2 antagonistsProstanoid receptor EP2 as a therapeutic targetAlantolactone, a natural sesquiterpene lactone, has potent antitumor activity against glioblastoma by targeting IKKβ kinase activity and interrupting NF-κB/COX-2-mediated signaling cascades.Development of second generation EP2 antagonists with high selectivityTherapeutic window for cyclooxygenase-2 related anti-inflammatory therapy after status epilepticusAberrant over-expression of COX-1 intersects multiple pro-tumorigenic pathways in high-grade serous ovarian cancerExpression of prostaglandin E2 prostanoid receptor EP2 and interleukin-1β in laryngeal carcinoma - preliminary studyEP2 Receptor Signaling Regulates Microglia Death.Food intake, tumor growth, and weight loss in EP2 receptor subtype knockout mice bearing PGE2-producing tumors.Inhibition of the prostaglandin receptor EP2 following status epilepticus reduces delayed mortality and brain inflammation.EP2 receptor signaling pathways regulate classical activation of microglia.Evaluation of WO 2012/177618 A1 and US-2014/0179750 A1: novel small molecule antagonists of prostaglandin-E2 receptor EP2.Repurposing Treprostinil for Enhancing Hematopoietic Progenitor Cell Transplantation.Discovery and characterization of carbamothioylacrylamides as EP2 selective antagonists.Anti-Inflammatory Small Molecules To Treat Seizures and Epilepsy: From Bench to BedsideDefining the therapeutic time window for suppressing the inflammatory prostaglandin E2 signaling after status epilepticus.Molecular mechanisms of target recognition by lipid GPCRs: relevance for cancer.Intracellular EP2 prostanoid receptor promotes cancer-related phenotypes in PC3 cells.Cyclooxygenase-2 in glioblastoma multiforme.Expression profiling of small intestinal neuroendocrine tumors identifies subgroups with clinical relevance, prognostic markers and therapeutic targets.PGE2 Promotes the Migration of Mesenchymal Stem Cells through the Activation of FAK and ERK1/2 Pathway.Melatonin potentiates the antitumor effect of curcumin by inhibiting IKKβ/NF-κB/COX-2 signaling pathway.Cyclooxygenase-2 contributes to oxidopamine-mediated neuronal inflammation and injury via the prostaglandin E2 receptor EP2 subtype.Rostral Ventrolateral Medulla EP3 Receptor Mediates the Sympathoexcitatory and Pressor Effects of Prostaglandin E2 in Conscious Rats.Prostaglandin E2 Signaling: Alternative Target for Glioblastoma?Intracrine prostaglandin E2 pro-tumoral actions in prostate epithelial cells originate from non-canonical pathways.The Treatment Landscape and New Opportunities of Molecular Targeted Therapies in Gastroenteropancreatic Neuroendocrine Tumors.Human DP and EP2 prostanoid receptors take on distinct forms depending on the diverse binding of different ligands.
P2860
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P2860
Role of prostaglandin receptor EP2 in the regulations of cancer cell proliferation, invasion, and inflammation.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Role of prostaglandin receptor ...... n, invasion, and inflammation.
@ast
Role of prostaglandin receptor ...... n, invasion, and inflammation.
@en
type
label
Role of prostaglandin receptor ...... n, invasion, and inflammation.
@ast
Role of prostaglandin receptor ...... n, invasion, and inflammation.
@en
prefLabel
Role of prostaglandin receptor ...... n, invasion, and inflammation.
@ast
Role of prostaglandin receptor ...... n, invasion, and inflammation.
@en
P2860
P356
P1476
Role of prostaglandin receptor ...... on, invasion, and inflammation
@en
P2093
Jianxiong Jiang
Ray Dingledine
P2860
P304
P356
10.1124/JPET.112.200444
P407
P577
2012-11-28T00:00:00Z