Improved therapeutic effect against leukemia by a combination of the histone methyltransferase inhibitor chaetocin and the histone deacetylase inhibitor trichostatin A.
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Epigenetic Therapy for Solid Tumors: Highlighting the Impact of Tumor HypoxiaTricyclic Analogues of Epidithiodioxopiperazine Alkaloids with Promising In Vitro and In Vivo Antitumor Activity.The SUV39H1 inhibitor chaetocin induces differentiation and shows synergistic cytotoxicity with other epigenetic drugs in acute myeloid leukemia cells.PU.1-Bim axis is involved in Trichostatin A-induced apoptosis in murine pro-B lymphoma FL5.12 cells.Strong Correlation between the Expression Levels of HDAC4 and SIRT6 in Hematological Malignancies of the Adults.Structure based design, synthesis and activity studies of small hybrid molecules as HDAC and G9a dual inhibitors.Molecular Pathways: Metabolic Control of Histone Methylation and Gene Expression in Cancer.Histone lysine methyltransferase SUV39H1 is a potent target for epigenetic therapy of hepatocellular carcinoma.
P2860
Q26783014-BB1FA691-660E-4C4E-BFAD-D2790BCCD7A6Q35753464-A6356439-D389-4FC1-95AB-48E5FCBE0379Q35764577-3210C685-5F10-46AC-9380-DE9E6A723B83Q38756171-8A5B67D9-C747-4E91-9429-C3DCBBC9AB11Q39264032-724940E8-27ED-417C-93A6-411151114E0FQ42064958-F26F7B3B-323E-4192-BE14-2C6F16479760Q46844610-259262F7-0BC4-463A-8A1F-CAA838325A57Q53049522-F3EAE287-2424-4BE9-85FF-19738AC20A80
P2860
Improved therapeutic effect against leukemia by a combination of the histone methyltransferase inhibitor chaetocin and the histone deacetylase inhibitor trichostatin A.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
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2013年论文
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name
Improved therapeutic effect ag ...... lase inhibitor trichostatin A.
@ast
Improved therapeutic effect ag ...... lase inhibitor trichostatin A.
@en
type
label
Improved therapeutic effect ag ...... lase inhibitor trichostatin A.
@ast
Improved therapeutic effect ag ...... lase inhibitor trichostatin A.
@en
prefLabel
Improved therapeutic effect ag ...... lase inhibitor trichostatin A.
@ast
Improved therapeutic effect ag ...... lase inhibitor trichostatin A.
@en
P2093
P2860
P1476
Improved therapeutic effect ag ...... lase inhibitor trichostatin A.
@en
P2093
Hee Nam Kim
Huong Thi Thanh Tran
Hyeoung-Joon Kim
Il-Kwon Lee
Jae-Sook Ahn
Je-Jung Lee
Kyeong-Soo Park
Thanh-Nhan Nguyen-Pham
Yeo-Kyeoung Kim
P2860
P304
P356
10.3346/JKMS.2013.28.2.237
P577
2013-01-29T00:00:00Z