about
NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemiaAberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemiaDiagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL)Epigenomics of leukemia: from mechanisms to therapeutic applicationsMyeloid malignancies: mutations, models and managementThe prognostic and functional role of microRNAs in acute myeloid leukemiaRNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemiaMultigene expression-based predictors for sensitivity to Vorinostat and Velcade in non-small cell lung cancer.Modulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectivesSouthwestern Oncology Group pretreatment risk criteria as predictive or prognostic factors in acute myeloid leukemiaMicroRNAs expression signatures are associated with lineage and survival in acute leukemias.Identification of nuclear-enriched miRNAs during mouse granulopoiesisPP2A inhibition from LB100 therapy enhances daunorubicin cytotoxicity in secondary acute myeloid leukemia via miR-181b-1 upregulation.Pathogenesis of ETV6/RUNX1-positive childhood acute lymphoblastic leukemia and mechanisms underlying its relapsemiR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemiaGenomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profilesComprehensive microRNA expression profiling of the hematopoietic hierarchy.Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia.Epigenome mapping reveals distinct modes of gene regulation and widespread enhancer reprogramming by the oncogenic fusion protein EWS-FLI1.Thrombomodulin as an intravascular safeguard against inflammatory and thrombotic diseases.Double CEBPA mutations are prognostically favorable in non-M3 acute myeloid leukemia patients with wild-type NPM1 and FLT3-ITD.C/EBPα regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutationsIncreased expression of miR-24 is associated with acute myeloid leukemia with t(8;21).Biology, risk stratification, and therapy of pediatric acute leukemias: an update.A phase I and pharmacodynamic study of the histone deacetylase inhibitor belinostat plus azacitidine in advanced myeloid neoplasia.Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells.The pathological role and prognostic impact of miR-181 in acute myeloid leukemiaGPX3 hypermethylation serves as an independent prognostic biomarker in non-M3 acute myeloid leukemia.Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML.Myeloid leukemia factor is a conserved regulator of RUNX transcription factor activity involved in hematopoiesis.Young intragenic miRNAs are less coexpressed with host genes than old ones: implications of miRNA-host gene coevolution.Identification of post-transcriptional regulatory networks during myeloblast-to-monocyte differentiation transition.Overexpression and knockout of miR-126 both promote leukemogenesisThe expression level of BAALC-associated microRNA miR-3151 is an independent prognostic factor in younger patients with cytogenetic intermediate-risk acute myeloid leukemia.Overexpression of miR-210 is Associated with Poor Prognosis of Acute Myeloid Leukemia.Differential regulation of cell death pathways by the microenvironment correlates with chemoresistance and survival in leukaemiaMiR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia.miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia.Improved therapeutic effect against leukemia by a combination of the histone methyltransferase inhibitor chaetocin and the histone deacetylase inhibitor trichostatin A.Identification of MLL-fusion/MYC⊣miR-26⊣TET1 signaling circuit in MLL-rearranged leukemia.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Leukaemogenesis: more than mutant genes
@ast
Leukaemogenesis: more than mutant genes
@en
Leukaemogenesis: more than mutant genes
@nl
type
label
Leukaemogenesis: more than mutant genes
@ast
Leukaemogenesis: more than mutant genes
@en
Leukaemogenesis: more than mutant genes
@nl
prefLabel
Leukaemogenesis: more than mutant genes
@ast
Leukaemogenesis: more than mutant genes
@en
Leukaemogenesis: more than mutant genes
@nl
P2093
P2860
P356
P1476
Leukaemogenesis: more than mutant genes
@en
P2093
Janet D Rowley
Jianjun Chen
Olatoyosi Odenike
P2860
P2888
P356
10.1038/NRC2765
P407
P577
2010-01-01T00:00:00Z
P5875
P6179
1021235678