Reinvigorating natural product combinatorial biosynthesis with synthetic biology
about
Accessing Nature's diversity through metabolic engineering and synthetic biologyRecent Advances in Understanding and Engineering Polyketide SynthesisBacterial genome engineering and synthetic biology: combating pathogensEndless Resistance. Endless Antibiotics?Sticky swinging arm dynamics: studies of an acyl carrier protein domain from the mycolactone polyketide synthaseCoalition of Biology and Chemistry for Ameliorating Antimicrobial Drug Discovery.Chemical probing of thiotetronate bio-assembly.Harnessing natural product assembly lines: structure, promiscuity, and engineering.Antibiotic discovery is a walk in the park.Engineered biosynthesis of milbemycins in the avermectin high-producing strain Streptomyces avermitilis.Heterologous biosynthesis and manipulation of crocetin in Saccharomyces cerevisiae.Recent advances in the biosynthesis of unusual polyketide synthase substrates.Profiling of Microbial Colonies for High-Throughput Engineering of Multistep Enzymatic Reactions via Optically Guided Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry.Nature's combinatorial biosynthesis and recently engineered production of nucleoside antibiotics in Streptomyces.Engineering microbial hosts for production of bacterial natural productsAn overview of rapamycin: from discovery to future perspectives.Comparative mass spectrometry-based metabolomics strategies for the investigation of microbial secondary metabolites.Biogenesis of antibiotics-viewing its history and glimpses of the future.Biosynthetic engineering of nonribosomal peptide synthetases.Azaepothilone B and its derivatives: a patent review.Insights into microbial cryptic gene activation and strain improvement: principle, application and technical aspects.Natural Products and the Gene Cluster Revolution.Genomic insights into specialized metabolism in the marine actinomycete Salinispora.Generate a bioactive natural product library by mining bacterial cytochrome P450 patterns.Omics-based natural product discovery and the lexicon of genome mining.Actinomycetes: still a source of novel antibiotics.Discovery of the leinamycin family of natural products by mining actinobacterial genomes.Synthetic biology, genome mining, and combinatorial biosynthesis of NRPS-derived antibiotics: a perspective.Diversifying Natural Products with Promiscuous Glycosyltransferase Enzymes via a Sustainable Microbial Fermentation Approach.Directing evolution: the next revolution in drug discovery?Expansion of chemical space for natural products by uncommon P450 reactions.Strategies to diversify natural products for drug discovery.Broadening substrate specificity of a chain-extending ketosynthase through a single active-site mutation.Exploiting nongenetic cell-to-cell variation for enhanced biosynthesis.Rapid generation of recombinant Pseudomonas putida secondary metabolite producers using yTREX.Nonribosomal biosynthesis of backbone-modified peptides.In silico exploration of Red Sea Bacillus genomes for natural product biosynthetic gene clusters.
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P2860
Reinvigorating natural product combinatorial biosynthesis with synthetic biology
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Reinvigorating natural product combinatorial biosynthesis with synthetic biology
@ast
Reinvigorating natural product combinatorial biosynthesis with synthetic biology
@en
type
label
Reinvigorating natural product combinatorial biosynthesis with synthetic biology
@ast
Reinvigorating natural product combinatorial biosynthesis with synthetic biology
@en
prefLabel
Reinvigorating natural product combinatorial biosynthesis with synthetic biology
@ast
Reinvigorating natural product combinatorial biosynthesis with synthetic biology
@en
P2860
P356
P1476
Reinvigorating natural product combinatorial biosynthesis with synthetic biology
@en
P2093
Yeo Joon Yoon
P2860
P2888
P304
P356
10.1038/NCHEMBIO.1893
P577
2015-09-01T00:00:00Z