Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17
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RNA helicase p68 (DDX5) regulates tau exon 10 splicing by modulating a stem-loop structure at the 5' splice siteCaspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's diseasePresenilin binding protein is associated with neurofibrillary alterations in Alzheimer's disease and stimulates tau phosphorylationMutations in tau gene exon 10 associated with FTDP-17 alter the activity of an exonic splicing enhancer to interact with Tra2 betaNMR Meets Tau: Insights into Its Function and PathologyMouse Genetic Models of Human Brain DisordersInvited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimagingTau-targeted treatment strategies in Alzheimer's diseaseDirect force measurements reveal that protein Tau confers short-range attractions and isoform-dependent steric stabilization to microtubules.Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17Structural Basis for Stabilization of the Tau Pre-mRNA Splicing Regulatory Element by Novantrone (Mitoxantrone)Comparative biochemistry of tau in progressive supranuclear palsy, corticobasal degeneration, FTDP-17 and Pick's diseaseClinicopathological correlations in corticobasal degenerationAlpha-synuclein and tau: teammates in neurodegeneration?Microtubule-dependent oligomerization of tau. Implications for physiological tau function and tauopathiesReduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutationsFrontotemporal Dementia.Alzheimer disease: a tale of two prionsA general modeling and visualization tool for comparing different members of a group: application to studying tau-mediated regulation of microtubule dynamics.FTDP-17 mutations in Tau alter the regulation of microtubule dynamics: an "alternative core" model for normal and pathological Tau action.Identification of novel susceptibility loci for Guam neurodegenerative disease: challenges of genome scans in genetic isolates.Tau isoform regulation is region- and cell-specific in mouse brain.MSUT2 is a determinant of susceptibility to tau neurotoxicityModulation of microtubule dynamics by tau in living cells: implications for development and neurodegenerationNeurofibrillary pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein.A new family with frontotemporal dementia with intronic 10+3 splice site mutation in the tau gene: neuropathology and molecular effects.Loss of brain tau defines novel sporadic and familial tauopathies with frontotemporal dementia.Two large British kindreds with familial Parkinson's disease: a clinico-pathological and genetic study.No evidence for association between tau gene haplotypic variants and susceptibility to Creutzfeldt-Jakob disease.Protein Quality Control and the Amyotrophic Lateral Sclerosis/Frontotemporal Dementia ContinuumFilamentous nerve cell inclusions in neurodegenerative diseases: tauopathies and alpha-synucleinopathies.Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy modelSNP detection using peptide nucleic acid probes and conjugated polymers: applications in neurodegenerative disease identificationFibrillogenesis of tau: insights from tau missense mutations in FTDP-17.Transgenic models of tauopathies and synucleinopathies.Tau levels do not influence human ALS or motor neuron degeneration in the SOD1G93A mouse.Complex genetics of amyotrophic lateral sclerosis.Aberrant splicing of tau pre-mRNA caused by intronic mutations associated with the inherited dementia frontotemporal dementia with parkinsonism linked to chromosome 17.Protein tau: prime cause of synaptic and neuronal degeneration in Alzheimer's disease.High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands
P2860
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P2860
Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Pathogenic implications of mut ...... orders linked to chromosome 17
@ast
Pathogenic implications of mut ...... orders linked to chromosome 17
@en
type
label
Pathogenic implications of mut ...... orders linked to chromosome 17
@ast
Pathogenic implications of mut ...... orders linked to chromosome 17
@en
prefLabel
Pathogenic implications of mut ...... orders linked to chromosome 17
@ast
Pathogenic implications of mut ...... orders linked to chromosome 17
@en
P2093
P2860
P356
P1476
Pathogenic implications of mut ...... orders linked to chromosome 17
@en
P2093
A Andreadis
D H Geschwind
G Schellenberg
J Q Trojanowski
K C Wilhelmsen
P2860
P304
13103-13107
P356
10.1073/PNAS.95.22.13103
P407
P577
1998-10-01T00:00:00Z