Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease
about
Tau Proteins and Neurofibrillary DegenerationThe kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinaseStimulatory effect of α-synuclein on the tau-phosphorylation by GSK-3βPhosphorylation of microtubule-associated protein tau by AMPK-related kinasesRNA helicase p68 (DDX5) regulates tau exon 10 splicing by modulating a stem-loop structure at the 5' splice siteInteraction of tau protein with the dynactin complexA role for FKBP52 in Tau protein functionThe low density lipoprotein receptor-related protein 6 interacts with glycogen synthase kinase 3 and attenuates activityLRRK2 phosphorylates tubulin-associated tau but not the free molecule: LRRK2-mediated regulation of the tau-tubulin association and neurite outgrowthIsoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer diseaseMicrotubule-associated protein/microtubule affinity-regulating kinase (p110mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262Protein kinase MARK/PAR-1 is required for neurite outgrowth and establishment of neuronal polarity.The human glutamate receptor cDNA GluR1: cloning, sequencing, expression and localization to chromosome 5Dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) modulates serine/arginine-rich protein 55 (SRp55)-promoted Tau exon 10 inclusionRegulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegenerationThe 3D profile method for identifying fibril-forming segments of proteinsSelective inhibition of Alzheimer disease-like tau aggregation by phenothiazinesHyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filamentsCurcumin and its derivatives: their application in neuropharmacology and neuroscience in the 21st centuryTransmission and spreading of tauopathy in transgenic mouse brainFunctional MAPT haplotypes: bridging the gap between genotype and neuropathologyalpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodiesHyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer diseasePresenilin binding protein is associated with neurofibrillary alterations in Alzheimer's disease and stimulates tau phosphorylationUltrastructure and biochemical composition of paired helical filaments in corticobasal degenerationMutations in tau gene exon 10 associated with FTDP-17 alter the activity of an exonic splicing enhancer to interact with Tra2 betaAntisense-mediated exon skipping: a versatile tool with therapeutic and research applicationsFamilial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filamentsThe MAP2/Tau family of microtubule-associated proteinsTemperature and toxic Tau in Alzheimer's disease: new insightsMolecular Mechanisms in the Pathogenesis of Alzheimer's disease and Tauopathies-Prion-Like Seeded Aggregation and PhosphorylationTau: The Center of a Signaling Nexus in Alzheimer's DiseaseCharacteristics of Tau and Its Ligands in PET ImagingTau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective StrategiesFrontotemporal lobar degeneration: old knowledge and new insight into the pathogenetic mechanisms of tau mutationsPhenotypic Heterogeneity of Monogenic Frontotemporal DementiaHuman fetal tau protein isoform: possibilities for Alzheimer's disease treatmentBrain-penetrant microtubule-stabilizing compounds as potential therapeutic agents for tauopathiesMicrotubule-stabilizing agents as potential therapeutics for neurodegenerative diseaseDeveloping therapeutic approaches to tau, selected kinases, and related neuronal protein targets
P2860
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P2860
Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease
description
1989 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1989
@ast
scientific journal article
@en
wetenschappelijk artikel (gepubliceerd op 1989/10/01)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована в жовтні 1989
@uk
مقالة علمية (نشرت في أكتوبر 1989)
@ar
name
Multiple isoforms of human mic ...... tangles of Alzheimer's disease
@ast
Multiple isoforms of human mic ...... tangles of Alzheimer's disease
@en
type
label
Multiple isoforms of human mic ...... tangles of Alzheimer's disease
@ast
Multiple isoforms of human mic ...... tangles of Alzheimer's disease
@en
prefLabel
Multiple isoforms of human mic ...... tangles of Alzheimer's disease
@ast
Multiple isoforms of human mic ...... tangles of Alzheimer's disease
@en
P2093
P921
P3181
P1433
P1476
Multiple isoforms of human mic ...... tangles of Alzheimer's disease
@en
P2093
D. Rutherford
M. G. Spillantini
M. Goedert
R. A. Crowther
P304
P3181
P356
10.1016/0896-6273(89)90210-9
P407
P577
1989-10-01T00:00:00Z