Complementation between polymerase- and exonuclease-deficient mitochondrial DNA polymerase mutants in genomically engineered flies.
about
MGME1 processes flaps into ligatable nicks in concert with DNA polymerase γ during mtDNA replication.Animal Mitochondrial DNA Replication.Cellular and population level processes influence the rate, accumulation and observed frequency of inherited and somatic mtDNA mutations.A multi-systemic mitochondrial disorder due to a dominant p.Y955H disease variant in DNA polymerase gamma.Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria.Autophagy balances mtDNA synthesis and degradation by DNA polymerase POLG during starvation.A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency.The Mitochondrial DNA Polymerase Promotes Elimination of Paternal Mitochondrial Genomes.Linear mitochondrial DNA is rapidly degraded by components of the replication machinery.Developmental arrest in Drosophila melanogaster caused by mitochondrial DNA replication defects cannot be rescued by the alternative oxidase
P2860
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P2860
Complementation between polymerase- and exonuclease-deficient mitochondrial DNA polymerase mutants in genomically engineered flies.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Complementation between polyme ...... genomically engineered flies.
@ast
Complementation between polyme ...... genomically engineered flies.
@en
type
label
Complementation between polyme ...... genomically engineered flies.
@ast
Complementation between polyme ...... genomically engineered flies.
@en
prefLabel
Complementation between polyme ...... genomically engineered flies.
@ast
Complementation between polyme ...... genomically engineered flies.
@en
P2093
P2860
P50
P921
P356
P1476
Complementation between polyme ...... genomically engineered flies.
@en
P2093
Ana Bratic
Bertil Macao
Francesca Baggio
Jacqueline Dols
Timo E S Kauppila
Triinu Siibak
P2860
P2888
P356
10.1038/NCOMMS9808
P407
P50
P577
2015-11-10T00:00:00Z
P5875
P6179
1007302572