The free fatty acid receptor G protein-coupled receptor 40 (GPR40) protects from bone loss through inhibition of osteoclast differentiation.
about
Fatty acid 16:4(n-3) stimulates a GPR120-induced signaling cascade in splenic macrophages to promote chemotherapy resistance.A gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40-MEK-ERK pathway.Bergapten prevents lipopolysaccharide mediated osteoclast formation, bone resorption and osteoclast survivalCloning, identification and functional characterization of bovine free fatty acid receptor-1 (FFAR1/GPR40) in neutrophils.The intestinal microbiome and skeletal fitness: Connecting bugs and bonesGPR120: A bi-potential mediator to modulate the osteogenic and adipogenic differentiation of BMMSCsDeficiency of G-protein coupled receptor 40, a lipid-activated receptor, heightens in vitro- and in vivo-induced murine osteoarthritis.Drugs or diet?--Developing novel therapeutic strategies targeting the free fatty acid family of GPCRsFat and bone interactions.Characterizing pharmacological ligands to study the long-chain fatty acid receptors GPR40/FFA1 and GPR120/FFA4.GPR40 agonists for the treatment of type 2 diabetes: life after 'TAKing' a hit.Agonist-induced activation of human FFA1 receptor signals to extracellular signal-regulated kinase 1 and 2 through Gq- and Gi-coupled signaling cascades.G protein-coupled receptor 84 controls osteoclastogenesis through inhibition of NF-κB and MAPK signaling pathways.The Role and Future of FFA1 as a Therapeutic Target.GPR40, a free fatty acid receptor, differentially impacts osteoblast behavior depending on differentiation stage and environment.PPARγ signaling and emerging opportunities for improved therapeutics.GPR40 mediates potential positive effects of a saturated fatty acid enriched diet on bone.Impact of a functionalized olive oil extract on the uterus and the bone in a model of postmenopausal osteoporosis.Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss.Pharmacological Tool Compounds for the Free Fatty Acid Receptor 4 (FFA4/GPR120).Psychosine inhibits osteoclastogenesis and bone resorption via G protein-coupled receptor 65.
P2860
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P2860
The free fatty acid receptor G protein-coupled receptor 40 (GPR40) protects from bone loss through inhibition of osteoclast differentiation.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
The free fatty acid receptor G ...... of osteoclast differentiation.
@ast
The free fatty acid receptor G ...... of osteoclast differentiation.
@en
type
label
The free fatty acid receptor G ...... of osteoclast differentiation.
@ast
The free fatty acid receptor G ...... of osteoclast differentiation.
@en
prefLabel
The free fatty acid receptor G ...... of osteoclast differentiation.
@ast
The free fatty acid receptor G ...... of osteoclast differentiation.
@en
P2093
P2860
P50
P356
P1476
The free fatty acid receptor G ...... of osteoclast differentiation
@en
P2093
Claire Philippe
Elisabeth Miot-Noirault
Fabien Wauquier
Laurent Léotoing
Marie-Jeanne Davicco
Patrice Lebecque
Paul Pilet
Sylvie Mercier
Véronique Coxam
Yohann Wittrant
P2860
P304
P356
10.1074/JBC.M112.429084
P407
P577
2013-01-18T00:00:00Z