The DegraBase: a database of proteolysis in healthy and apoptotic human cells
about
Caspases uncouple p27(Kip1) from cell cycle regulated degradation and abolish its ability to stimulate cell migration and invasionProteomic Substrate Identification for Membrane Proteases in the BrainQuantitative proteomics and terminomics to elucidate the role of ubiquitination and proteolysis in adaptive immunityDNA sensor cGAS-mediated immune recognitionCleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death.Determinants of Macromolecular Specificity from Proteomics-Derived Peptide Substrate Data.An unbiased proteomic screen reveals caspase cleavage is positively and negatively regulated by substrate phosphorylationN-terminal proteomics and ribosome profiling provide a comprehensive view of the alternative translation initiation landscape in mice and menMS-viewer: a web-based spectral viewer for proteomics results.Circulating proteolytic signatures of chemotherapy-induced cell death in humans discovered by N-terminal labeling.Caspase cleavage sites in the human proteome: CaspDB, a database of predicted substrates.Unraveling the mechanism of cell death induced by chemical fibrils.Global analysis of cellular proteolysis by selective enzymatic labeling of protein N-termini.MitoFates: improved prediction of mitochondrial targeting sequences and their cleavage sites.Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.Human ACAP2 is a homolog of C. elegans CNT-1 that promotes apoptosis in cancer cellsDegradation of the Separase-cleaved Rec8, a Meiotic Cohesin Subunit, by the N-end Rule Pathway.Quantitative MS-based enzymology of caspases reveals distinct protein substrate specificities, hierarchies, and cellular roles.Global cellular response to chemotherapy-induced apoptosis.Proteolytic post-translational modification of proteins: proteomic tools and methodology.The novel caspase-3 substrate Gap43 is involved in AMPA receptor endocytosis and long-term depressionCaspNeuroD: a knowledgebase of predicted caspase cleavage sites in human proteins related to neurodegenerative diseases.Interactome disassembly during apoptosis occurs independent of caspase cleavage.Proteomic identification of protease cleavage sites: cell-biological and biomedical applications.Proteomic tools for the characterization of cell death mechanisms in drug discovery.Twenty years of the MEROPS database of proteolytic enzymes, their substrates and inhibitors.Comprehensive analysis of human protein N-termini enables assessment of various protein forms.Comparative Analysis of Mitochondrial N-Termini from Mouse, Human, and Yeast.Caspases rule the intracellular trafficking cartel.Ferroptosis: bug or feature?Caspases and their substrates.Caspases control antiviral innate immunity.The path of no return--Truncated protein N-termini and current ignorance of their genesis.Cacidases: caspases can cleave after aspartate, glutamate and phosphoserine residues.Caspases play in trafficCaspase-mediated proteolysis of the sorting nexin 2 disrupts retromer assembly and potentiates Met/hepatocyte growth factor receptor signaling.Protease cleavage site fingerprinting by label-free in-gel degradomics reveals pH-dependent specificity switch of legumain.Quantitative peptidomics of endogenous peptides involved in TGF-β1-induced epithelial mesenchymal transition of renal epithelial cells.Caspase-mediated cleavage of the centrosomal proteins during apoptosis.The Role of Apoptotic Signaling in Axon Guidance
P2860
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P2860
The DegraBase: a database of proteolysis in healthy and apoptotic human cells
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
The DegraBase: a database of proteolysis in healthy and apoptotic human cells
@ast
The DegraBase: a database of proteolysis in healthy and apoptotic human cells
@en
type
label
The DegraBase: a database of proteolysis in healthy and apoptotic human cells
@ast
The DegraBase: a database of proteolysis in healthy and apoptotic human cells
@en
prefLabel
The DegraBase: a database of proteolysis in healthy and apoptotic human cells
@ast
The DegraBase: a database of proteolysis in healthy and apoptotic human cells
@en
P2093
P2860
P921
P356
P1476
The DegraBase: a database of proteolysis in healthy and apoptotic human cells
@en
P2093
Emily D Crawford
Gerald W Hsu
Hikari A I Yoshihara
Huy Nguyen
James A Wells
Julia E Seaman
Kazutaka Shimbo
Min Zhuang
Nick Agard
Sami Mahrus
P2860
P304
P356
10.1074/MCP.O112.024372
P577
2012-12-20T00:00:00Z