A novel small-molecule inhibitor of influenza A virus acts by suppressing PA endonuclease activity of the viral polymerase.
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The Influenza Virus Polymerase Complex: An Update on Its Structure, Functions, and Significance for Antiviral Drug DesignProgress of small molecular inhibitors in the development of anti-influenza virus agents.Influenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis.Identification of Novel and Efficacious Chemical Compounds that Disturb Influenza A Virus Entry in vitroN-acylhydrazone inhibitors of influenza virus PA endonuclease with versatile metal binding modes.Amino acid substitutions V63I or A37S/I61T/V63I/V100A in the PA N-terminal domain increase the virulence of H7N7 influenza A virus.Arabidopsis thaliana Acyl-CoA-Binding Protein ACBP6 Interacts with Plasmodesmata-Located Protein PDLP8.The PA Endonuclease Inhibitor RO-7 Protects Mice from Lethal Challenge with Influenza A or B Viruses.
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P2860
A novel small-molecule inhibitor of influenza A virus acts by suppressing PA endonuclease activity of the viral polymerase.
description
2016 nî lūn-bûn
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2016年の論文
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2016年論文
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name
A novel small-molecule inhibit ...... ivity of the viral polymerase.
@ast
A novel small-molecule inhibit ...... ivity of the viral polymerase.
@en
type
label
A novel small-molecule inhibit ...... ivity of the viral polymerase.
@ast
A novel small-molecule inhibit ...... ivity of the viral polymerase.
@en
prefLabel
A novel small-molecule inhibit ...... ivity of the viral polymerase.
@ast
A novel small-molecule inhibit ...... ivity of the viral polymerase.
@en
P2093
P2860
P356
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A novel small-molecule inhibit ...... tivity of the viral polymerase
@en
P2093
Bo-Jian Zheng
Hanjun Zhao
Kailash Singh
Richard Y T Kao
Shuofeng Yuan
P2860
P2888
P356
10.1038/SREP22880
P407
P577
2016-03-09T00:00:00Z