Variation in MAPT is associated with cerebrospinal fluid tau levels in the presence of amyloid-beta deposition.
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SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer's diseaseDiagnosis-independent Alzheimer disease biomarker signature in cognitively normal elderly peopleGenetic variants associated with neurodegenerative Alzheimer disease in natural modelsThree dimensions of the amyloid hypothesis: time, space and 'wingmen'Molecular profiling reveals diversity of stress signal transduction cascades in highly penetrant Alzheimer's disease human skin fibroblastsGWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.Origins of Alzheimer's disease: reconciling cerebrospinal fluid biomarker and neuropathology data regarding the temporal sequence of amyloid-beta and tau involvement.Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels.The PSEN1, p.E318G variant increases the risk of Alzheimer's disease in APOE-ε4 carriersAn epigenetic signature in peripheral blood associated with the haplotype on 17q21.31, a risk factor for neurodegenerative tauopathy.Biomarkers in translational research of Alzheimer's diseaseCerebrospinal fluid biomarkers of Alzheimer's disease.Transgenic Drosophila models of Alzheimer's disease and tauopathiesFine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's diseaseTargeting Abeta and tau in Alzheimer's disease, an early interim reportTau Ser262 phosphorylation is critical for Abeta42-induced tau toxicity in a transgenic Drosophila model of Alzheimer's disease.Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammationAlzheimer's disease risk genes and mechanisms of disease pathogenesisValidating predicted biological effects of Alzheimer's disease associated SNPs using CSF biomarker levelsGenetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort.Association of TMEM106B gene polymorphism with age at onset in granulin mutation carriers and plasma granulin protein levels.Association and expression analyses with single-nucleotide polymorphisms in TOMM40 in Alzheimer disease.Regulation of human MAPT gene expression.Fluid biomarkers in Alzheimer disease.Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's diseaseExtracellular Tau levels are influenced by variability in Tau that is associated with tauopathies.Finding risk in all the right placesAntisense reduction of tau in adult mice protects against seizuresAn inflection point in gene discovery efforts for neurodegenerative diseases: from syndromic diagnoses toward endophenotypes and the epigenome.Genetic control of human brain transcript expression in Alzheimer disease.Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects.Longitudinal assessment of tau and amyloid beta in cerebrospinal fluid of Parkinson diseaseVariants in PPP3R1 and MAPT are associated with more rapid functional decline in Alzheimer's disease: the Cache County Dementia Progression Study.Genome sequencing in a case of Niemann-Pick type CCalcium phosphatase calcineurin influences tau metabolism.Critical issues for successful immunotherapy in Alzheimer's disease: development of biomarkers and methods for early detection and intervention.Genetic discoveries in AD using CSF amyloid and tau.Alzheimer's disease: the challenge of the second century.CSF biomarkers for amyloid and tau pathology in Alzheimer's disease.Alternative Approaches in Gene Discovery and Characterization in Alzheimer's Disease.
P2860
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P2860
Variation in MAPT is associated with cerebrospinal fluid tau levels in the presence of amyloid-beta deposition.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Variation in MAPT is associate ...... ce of amyloid-beta deposition.
@ast
Variation in MAPT is associate ...... ce of amyloid-beta deposition.
@en
type
label
Variation in MAPT is associate ...... ce of amyloid-beta deposition.
@ast
Variation in MAPT is associate ...... ce of amyloid-beta deposition.
@en
prefLabel
Variation in MAPT is associate ...... ce of amyloid-beta deposition.
@ast
Variation in MAPT is associate ...... ce of amyloid-beta deposition.
@en
P2093
P2860
P50
P356
P1476
Variation in MAPT is associate ...... ce of amyloid-beta deposition.
@en
P2093
John S K Kauwe
Kevin Mayo
Petra Nowotny
Sarah Bertelsen
P2860
P304
P356
10.1073/PNAS.0801227105
P407
P50
P577
2008-06-09T00:00:00Z