Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation
about
The evolution within usIntegrative systems medicine approaches to identify molecular targets in lymphoid malignanciesComplex and multi-allelic copy number variation in human diseaseProduction of individualized V gene databases reveals high levels of immunoglobulin genetic diversityAutomated analysis of high-throughput B-cell sequencing data reveals a high frequency of novel immunoglobulin V gene segment alleles.A Database of Human Immune Receptor Alleles Recovered from Population Sequencing Data.Molecular signatures of hemagglutinin stem-directed heterosubtypic human neutralizing antibodies against influenza A viruses.Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assemblyAssociation between a common immunoglobulin heavy chain allele and rheumatic heart disease risk in Oceania.The promise and challenge of high-throughput sequencing of the antibody repertoire.Hypothesis exploration with visualization of varianceImmunoglobulin heavy chain variable region and major histocompatibility region genes are linked to induced graves' disease in females from two very large families of recombinant inbred miceSoma-to-germline feedback is implied by the extreme polymorphism at IGHV relative to MHC: The manifest polymorphism of the MHC appears greatly exceeded at Immunoglobulin loci, suggesting antigen-selected somatic V mutants penetrate Weismann's BarrieSingle haplotype assembly of the human genome from a hydatidiform moleSequencing of the human IG light chain loci from a hydatidiform mole BAC library reveals locus-specific signatures of genetic diversityExtending reference assembly models.IgE-associated IGHV genes from venom and peanut allergic individuals lack mutational evidence of antigen selection.Rheumatoid arthritis response to treatment across IgG1 allotype - anti-TNF incompatibility: a case-only studyNovel exons and splice variants in the human antibody heavy chain identified by single cell and single molecule sequencing.Ability to develop broadly neutralizing HIV-1 antibodies is not restricted by the germline Ig gene repertoire.The mouse antibody heavy chain repertoire is germline-focused and highly variable between inbred strains.A Public Database of Memory and Naive B-Cell Receptor SequencesEstimating Copy Number and Allelic Variation at the Immunoglobulin Heavy Chain Locus Using Short Reads.DJ Pairing during VDJ Recombination Shows Positional Biases That Vary among Individuals with Differing IGHD Locus ImmunogenotypesIGHV1-69 polymorphism modulates anti-influenza antibody repertoires, correlates with IGHV utilization shifts and varies by ethnicityExtensive load of somatic CNVs in the human placenta.The shape of the lymphocyte receptor repertoire: lessons from the B cell receptorDeep sequencing and human antibody repertoire analysis.Critical review of NGS analyses for de novo genotyping multigene families.Sequencing the functional antibody repertoire--diagnostic and therapeutic discovery.Adaptive potential of genomic structural variation in human and mammalian evolution.The Individual and Population Genetics of Antibody Immunity.Cynomolgus macaque (Macaca fascicularis) immunoglobulin heavy chain locus description.Reconstructing and mining the B cell repertoire with ImmunediveRsityA Streamlined Approach to Antibody Novel Germline Allele Prediction and Validation.Diversity in the preimmune immunoglobulin repertoire of SHR lines susceptible and resistant to end-organ injury.Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CAImmunoglobulin heavy variable (IGHV) genes and alleles: new entities, new names and implications for research and prognostication in chronic lymphocytic leukaemia.Reproducibility and Reuse of Adaptive Immune Receptor Repertoire Data.The antibody loci of the domestic goat (Capra hircus).
P2860
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P2860
Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Complete haplotype sequence of ...... elic and copy-number variation
@ast
Complete haplotype sequence of ...... elic and copy-number variation
@en
type
label
Complete haplotype sequence of ...... elic and copy-number variation
@ast
Complete haplotype sequence of ...... elic and copy-number variation
@en
prefLabel
Complete haplotype sequence of ...... elic and copy-number variation
@ast
Complete haplotype sequence of ...... elic and copy-number variation
@en
P2093
P2860
P1476
Complete haplotype sequence of ...... elic and copy-number variation
@en
P2093
A Jeremy Willsey
Corey T Watson
Evan E Eichler
Felix Breden
Jacqueline Schein
Jamie K Scott
Jeffrey B Joy
John Huddleston
Karyn M Steinberg
Maika Malig
P2860
P304
P356
10.1016/J.AJHG.2013.03.004
P407
P577
2013-03-28T00:00:00Z