Immunoglobulin heavy variable (IGHV) genes and alleles: new entities, new names and implications for research and prognostication in chronic lymphocytic leukaemia.
about
Integrative systems medicine approaches to identify molecular targets in lymphoid malignanciesAutomated analysis of high-throughput B-cell sequencing data reveals a high frequency of novel immunoglobulin V gene segment alleles.IMPre: An Accurate and Efficient Software for Prediction of T- and B-Cell Receptor Germline Genes and Alleles from Rearranged Repertoire Data.Immunoglobulins: 25 years of immunoinformatics and IMGT-ONTOLOGY.The outcome of Chronic lymphocytic leukaemia patients with 97% IGHV gene identity to germline is distinct from cases with <97% identity and similar to those with 98% identity.Preferential Usage of Specific Immunoglobulin Heavy Chain Variable Region Genes With Unmutated Profile and Advanced Stage at Presentation Are Common Features in Patients With Chronic Lymphocytic Leukemia From Senegal.The absolute percent deviation of IGHV mutation rather than a 98% cut-off predicts survival of chronic lymphocytic leukaemia patients treated with fludarabine, cyclophosphamide and rituximab.Comment on "A Database of Human Immune Receptor Alleles Recovered from Population Sequencing Data".
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Immunoglobulin heavy variable (IGHV) genes and alleles: new entities, new names and implications for research and prognostication in chronic lymphocytic leukaemia.
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2014 nî lūn-bûn
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name
Immunoglobulin heavy variable ...... chronic lymphocytic leukaemia.
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Immunoglobulin heavy variable ...... chronic lymphocytic leukaemia.
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type
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Immunoglobulin heavy variable ...... chronic lymphocytic leukaemia.
@en
Immunoglobulin heavy variable ...... chronic lymphocytic leukaemia.
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Immunoglobulin heavy variable ...... chronic lymphocytic leukaemia.
@en
Immunoglobulin heavy variable ...... chronic lymphocytic leukaemia.
@nl
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Immunoglobulin heavy variable ...... chronic lymphocytic leukaemia.
@en
P2093
Alessandra Tedeschi
Aliki Xochelli
Anastasia Hadzidimitriou
Andreas Agathangelidis
Anton W Langerak
Christian Geisler
Chrysoula Belessi
David Oscier
Diane F Jelinek
Evangelia Minga
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P2888
P356
10.1007/S00251-014-0812-3
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2014-11-12T00:00:00Z