In Vitro Biosynthesis of the Core Scaffold of the Thiopeptide Thiomuracin
about
Elucidating and engineering thiopeptide biosynthesis.Capture of micrococcin biosynthetic intermediates reveals C-terminal processing as an obligatory step for in vivo maturation.An α/β-hydrolase fold protein in the biosynthesis of thiostrepton exhibits a dual activity for endopeptidyl hydrolysis and epoxide ring opening/macrocyclization.YcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and Function.Ribosomally synthesized and post-translationally modified peptide natural product discovery in the genomic era.Cameo appearances of aminoacyl-tRNA in natural product biosynthesis.Mechanistic Understanding of Lanthipeptide Biosynthetic Enzymes.Post-translational modifications involved in the biosynthesis of thiopeptide antibiotics.Natural [4 + 2]-Cyclases.Reconstitution and Minimization of a Micrococcin Biosynthetic Pathway in Bacillus subtilis.Biosynthesis of the nosiheptide indole side ring centers on a cryptic carrier protein NosJ.Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo.Biochemical Characterization of a Eukaryotic Decalin-Forming Diels-AlderaseMutagenesis of NosM Leader Peptide Reveals Important Elements in Nosiheptide BiosynthesisBiosynthetic Timing and Substrate Specificity for the Thiopeptide Thiomuracin.Structural insights into enzymatic [4+2] aza-cycloaddition in thiopeptide antibiotic biosynthesis.Radical S-Adenosylmethionine Enzymes Involved in RiPP Biosynthesis.Ribosomal Natural Products, Tailored To Fit.Identification and characterization of a bacterial cytochrome P450 monooxygenase catalyzing the 3-nitration of tyrosine in rufomycin biosynthesis.Reconstitution and Substrate Specificity of the Radical S-Adenosyl-methionine Thiazole C-Methyltransferase in Thiomuracin Biosynthesis.Investigation of the mechanism of the SpnF-catalyzed [4+2]-cycloaddition reaction in the biosynthesis of spinosyn A.Mechanism of a Class C Radical S-Adenosyl-l-methionine Thiazole Methyl Transferase.Rerouting the Pathway for the Biosynthesis of the Side Ring System of Nosiheptide: The Roles of NosI, NosJ, and NosK.RiPP antibiotics: biosynthesis and engineering potential.A distributive peptide cyclase processes multiple microviridin core peptides within a single polypeptide substrate.
P2860
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P2860
In Vitro Biosynthesis of the Core Scaffold of the Thiopeptide Thiomuracin
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
In Vitro Biosynthesis of the Core Scaffold of the Thiopeptide Thiomuracin
@ast
In Vitro Biosynthesis of the Core Scaffold of the Thiopeptide Thiomuracin
@en
type
label
In Vitro Biosynthesis of the Core Scaffold of the Thiopeptide Thiomuracin
@ast
In Vitro Biosynthesis of the Core Scaffold of the Thiopeptide Thiomuracin
@en
prefLabel
In Vitro Biosynthesis of the Core Scaffold of the Thiopeptide Thiomuracin
@ast
In Vitro Biosynthesis of the Core Scaffold of the Thiopeptide Thiomuracin
@en
P2860
P50
P356
P1476
In Vitro Biosynthesis of the Core Scaffold of the Thiopeptide Thiomuracin
@en
P2093
Graham A Hudson
Zhengan Zhang
P2860
P304
16012-16015
P356
10.1021/JACS.5B10194
P407
P577
2015-12-21T00:00:00Z