Molecular anatomy of antigen-specific CD8(+) T cell engagement and synapse formation in vivo.
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Use of HLA-B27 tetramers to identify low-frequency antigen-specific T cells in Chlamydia-triggered reactive arthritis.Therapeutic antiviral T cells noncytopathically clear persistently infected microglia after conversion into antigen-presenting cellsIlluminating viral infections in the nervous systemVisualization of cytolytic T cell differentiation and granule exocytosis with T cells from mice expressing active fluorescent granzyme BT-cell receptor- and CD28-induced Vav1 activity is required for the accumulation of primed T cells into antigenic tissue.High avidity CD8+ T cells efficiently eliminate motile HIV-infected targets and execute a locally focused program of anti-viral functionThree phases of CD8 T cell response in the lung following H1N1 influenza infection and sphingosine 1 phosphate agonist therapyDynamics of CD8+ T cell priming by dendritic cells in intact lymph nodesLow T cell receptor expression and thermal fluctuations contribute to formation of dynamic multifocal synapses in thymocytes.Cytotoxic T lymphocytes kill multiple targets simultaneously via spatiotemporal uncoupling of lytic and stimulatory synapses.Subcellular dynamics of T cell immunological synapses and kinapses in lymph nodes.In situ imaging of the endogenous CD8 T cell response to infection.High-resolution, noninvasive longitudinal live imaging of immune responsesA model for the interplay of receptor recycling and receptor-mediated contact in T cellsFunctional glycosylation of dystroglycan is crucial for thymocyte development in the mouseKupfer-type immunological synapse characteristics do not predict anti-brain tumor cytolytic T-cell function in vivo.Herpes simplex virus-specific memory CD8+ T cells are selectively activated and retained in latently infected sensory gangliaThe synapse and cytolytic machinery of cytotoxic T cells.A broadly applicable approach to T cell epitope identification: application to improving tumor associated epitopes and identifying epitopes in complex pathogens.Rapid formation of extended processes and engagement of Theiler's virus-infected neurons by CNS-infiltrating CD8 T cells.Cytotoxic immunological synapses.Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients.Real-time analysis of T cell receptors in naive cells in vitro and in vivo reveals flexibility in synapse and signaling dynamics.Molecular anatomy and number of antigen specific CD8 T cells required to cause type 1 diabetesDisruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice.Migration of cytotoxic lymphocytes in cell cycle permits local MHC I-dependent control of division at sites of viral infectionQuantitative analysis of the role of receptor recycling in T cell polarization.Clearance of an immunosuppressive virus from the CNS coincides with immune reanimation and diversification.Dangerous liaisons at the virological synapse.Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity.IP-10 and type 1 diabetes: a question of time and location.In vivo mature immunological synapses forming SMACs mediate clearance of virally infected astrocytes from the brainRandom migration precedes stable target cell interactions of tumor-infiltrating T cells.Adoptive immunotherapy induces CNS dendritic cell recruitment and antigen presentation during clearance of a persistent viral infectionThe role of bystander T cells in CNS pathology and pathogen clearance.Virus-specific CD8+ T cells accumulate near sensory nerve endings in genital skin during subclinical HSV-2 reactivation.Live imaging of effector cell trafficking and autoantigen recognition within the unfolding autoimmune encephalomyelitis lesion.Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes.Treatment with anti-LFA-1 delays the CD8+ cytotoxic-T-lymphocyte response and viral clearance in mice with primary respiratory syncytial virus infection.PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis
P2860
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P2860
Molecular anatomy of antigen-specific CD8(+) T cell engagement and synapse formation in vivo.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Molecular anatomy of antigen-s ...... and synapse formation in vivo.
@en
type
label
Molecular anatomy of antigen-s ...... and synapse formation in vivo.
@en
prefLabel
Molecular anatomy of antigen-s ...... and synapse formation in vivo.
@en
P2093
P2860
P356
P1433
P1476
Molecular anatomy of antigen-s ...... and synapse formation in vivo.
@en
P2093
Dorian B McGavern
Michael B A Oldstone
Urs Christen
P2860
P304
P356
10.1038/NI843
P407
P577
2002-09-23T00:00:00Z